{"id":3692,"date":"2025-05-30T15:26:15","date_gmt":"2025-05-30T19:26:15","guid":{"rendered":"https:\/\/carleton.ca\/biochem\/?post_type=cu_people&p=3692"},"modified":"2025-05-30T15:26:18","modified_gmt":"2025-05-30T19:26:18","slug":"iain-mckinnell","status":"publish","type":"cu_people","link":"https:\/\/carleton.ca\/biochem\/people\/iain-mckinnell\/","title":{"rendered":"Iain McKinnell"},"content":{"rendered":"
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\n \n \n \n <\/h1>\n\n \n <\/header>\n\n\n\n\n\n

Current Research<\/h3>\n\n\n\n

My interests lie in the processes of embryological development \u2013 in particular their molecular regulation \u2013 and how these processes contribute to the anatomy and physiology of animals.<\/p>\n\n\n\n

Selected Publications<\/h3>\n\n\n\n

Arnaout B, MacKenzie EM, Lantigua KE, Brzezinski K, McKinnell IW<\/strong>, Maddin HC. (2022) The histology of sutures in chicken skulls: Types, conservation, and ontogeny. J Anat.;240(3):503-515. doi: 10.1111\/joa.13574. PMID: 34668205<\/p>\n\n\n\n

MacKenzie EM, Atkins JB, Korneisel DE, Cantelon AS, McKinnell IW<\/strong>, Maddin HC. (2021) Normal development in Xenopus laevis: A complementary staging table for the skull based on cartilage and bone. Dev Dyn.; 251(8):1340-1356. doi: 10.1002\/dvdy.465.<\/p>\n\n\n\n

Arnaout B, Lantigua KE, MacKenzie EM, McKinnell IW<\/strong>, Maddin HC (2021) Development of the chicken skull: A complement to the external staging table of Hamburger and Hamilton. Anat Rec, Feb 23. doi: 10.1002\/ar.24603.<\/p>\n\n\n\n

Kawabe Y, Wang YX, McKinnell IW<\/strong>, Bedford MT, Rudnicki MA. (2012) Carm1 regulates Pax7 transcriptional activity through MLL1\/2 recruitment during asymmetric satellite stem cell divisions. Cell Stem Cell.;11(3):333-45. doi: 10.1016\/j.stem.2012.07.001.<\/p>\n\n\n\n

Smith B, Treadwell J, Zhang D, Ly D, McKinnell I<\/strong>, Walker PR & Sikorska M. (2010) Large scale expression analysis reveals distinct miRNA profiles at different stages of human neurodevelopment. PLoS One; 5(6): e11109.<\/p>\n\n\n\n

McKinnell IW<\/strong>, Ishibashi J, LeGrand F, Punch V, Addicks G,  Greenblatt J, Dilworth J, Rudnicki MA (2008) Pax7 regulates myogenic genes via recruitment of a histone methyltransferase complex. Nature Cell Biology; 10: 77-84 .<\/p>\n\n\n\n

McKinnell I*<\/strong>, Krishan K*, Patel K, Dhoot GK. (2005) Dynamic ID2 expression in the medial and lateral domains of avian dermomytome. Developmental Dynamics; 234: 363-70.<\/p>\n\n\n\n

McKinnell IW<\/strong>, Turmaine M, Patel K. (2004) Sonic Hedgehog functions by localizing the region of proliferation in early developing feather buds. Developmental Biology; 272: 76-88<\/p>\n\n\n\n

McKinnell IW<\/strong>, Makarenkova H, de Curtis I, Turmaine M, Patel K. (2004) EphA4, RhoB and the molecular development of feather buds are maintained by the integrity of the actin cytoskeleton. Developmental Biology; 270: 94-105.<\/p>\n\n\n\n

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