{"id":3938,"date":"2025-06-04T10:47:55","date_gmt":"2025-06-04T14:47:55","guid":{"rendered":"https:\/\/carleton.ca\/biochem\/?post_type=cu_people&#038;p=3938"},"modified":"2025-06-13T10:03:12","modified_gmt":"2025-06-13T14:03:12","slug":"david-sabatino","status":"publish","type":"cu_people","link":"https:\/\/carleton.ca\/biochem\/people\/david-sabatino\/","title":{"rendered":"David Sabatino"},"content":{"rendered":"<header class=\"mb-6 cu-pageheader cu-component-updated md:mb-12\">\n    <h1 class=\"cu-prose-first-last font-semibold !mt-2 mb-4 md:mb-6 text-3xl md:text-4xl lg:text-5xl lg:leading-[3.5rem] relative after:absolute after:h-px after:bottom-0 pb-5 after:w-10 after:bg-cu-red after:left-px\">\n                    \n             \n                \n            <\/h1>\n\n    \n    <\/header>\n\n\n\n\n\n<h3 id=\"current-research\" class=\"wp-block-heading\">Current Research<\/h3>\n\n\n\n<p>My research interests spans the areas of nucleic acid, peptide and protein chemical biology for developing synthetic biologicals for applications in drug discovery related to anti-cancer activity.<\/p>\n\n\n\n<h3 id=\"selected-publications\" class=\"wp-block-heading\">Selected Publications<\/h3>\n\n\n\n<p>1.George Hilan, Grace Daniel, Filiz Collak, William Willmore, Bruce McKay and David Sabatino. Cancer-Targeting Peptides Functionalized with Polyarginine Enables GRP78-Dependent Cell Uptake and siRNA Delivery within the DU145 Prostate Cancer Cells. <em>J. Pept. Sci. <\/em>2025, <em>31<\/em>(3), e70007.<\/p>\n\n\n\n<p>2. <a>Grace Daniel, George Hilan, Lisa Ploeg and <u>David Sabatino.<\/u> Self-Assembly of Helical-Coiled Amphiphilic Peptide Nanofibers and Inhibition of Fibril Formation by Curcumin. <em>Bioorg. Med. Chem. Lett.<\/em>, 2024; <\/a><em>102<\/em>, 129682.<\/p>\n\n\n\n<p>3. Nour Nissan, Mitchell Allen, David Sabatino and Kyle Biggar Future Perspective: Harnessing the Power of Artificial Intelligence in the Generation of New Peptide Drugs. <em>Biomolecules. <\/em>2024, <em>14<\/em>(10), 1303.<\/p>\n\n\n\n<p>4. Dante Descalzi-Montoya, Rachel A. Montel, Keith Smith, Eugenia Dziopa, Andrieh Darwich, Zheng Yang, Constantine Bitsaktsis, Robert Korngold, and David Sabatino.Synthetic Antibody Mimics Based on Cancer-Targeting Immunostimulatory Peptides. <em>ChemBioChem.<\/em> 2021, <em>22<\/em>(9), 1589-1596.<\/p>\n\n\n\n<p>5. David Sabatino. Medicinal Chemistry and Methodological Advances in Peptide-Based Vaccines. <em>J. Med. Chem<\/em>. 2020, <em>63<\/em>(23),14184-14196.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"author":261,"featured_media":1737,"template":"","meta":{"_acf_changed":false,"cu_people_first_name":"David","cu_people_last_name":"Sabatino","cu_people_initials":"DS","footnotes":"","_links_to":"","_links_to_target":""},"cu_people_type":[27],"cu_people_expertise":[],"class_list":["post-3938","cu_people","type-cu_people","status-publish","has-post-thumbnail","hentry","cu_people_type-faculty"],"acf":{"cu_people_job_title":"Associate Professor","cu_people_degree":"Ph.D (McGill University)","cu_building":"SC","cu_people_office_num":"207F","cu_people_pronoun":"","cu_people_designation":"","cu_people_email":"david.sabatino@carleton.ca","cu_people_phone":"613-520-2600","cu_people_phone_ext":"4229","cu_people_linkedin":"","cu_people_bluesky":"","cu_people_twitter":"","cu_people_instagram":"","cu_people_facebook":"","cu_people_website":"https:\/\/carleton.ca\/sabatinolab\/","cu_people_orcid":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/cu_people\/3938","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/cu_people"}],"about":[{"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/types\/cu_people"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/users\/261"}],"version-history":[{"count":2,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/cu_people\/3938\/revisions"}],"predecessor-version":[{"id":3991,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/cu_people\/3938\/revisions\/3991"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/media\/1737"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/media?parent=3938"}],"wp:term":[{"taxonomy":"cu_people_type","embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/cu_people_type?post=3938"},{"taxonomy":"cu_people_expertise","embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/cu_people_expertise?post=3938"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}