{"id":1535,"date":"2021-01-20T10:28:31","date_gmt":"2021-01-20T15:28:31","guid":{"rendered":"https:\/\/carleton.ca\/biochem\/?p=1535"},"modified":"2025-05-01T12:05:00","modified_gmt":"2025-05-01T16:05:00","slug":"towards-a-cure-carleton-research-team-working-on-stem-cell-therapy-to-reverse-type-1-diabetes","status":"publish","type":"post","link":"https:\/\/carleton.ca\/biochem\/2021\/towards-a-cure-carleton-research-team-working-on-stem-cell-therapy-to-reverse-type-1-diabetes\/","title":{"rendered":"Towards a Cure: Carleton Research Team Working on Stem Cell Therapy to Reverse Type 1 Diabetes"},"content":{"rendered":"\n<section class=\"w-screen px-6 cu-section cu-section--white ml-offset-center md:px-8 lg:px-14\">\n    <div class=\"space-y-6 cu-max-w-child-5xl  md:space-y-10 cu-prose-first-last\">\n\n            <div class=\"cu-textmedia flex flex-col lg:flex-row mx-auto gap-6 md:gap-10 my-6 md:my-12 first:mt-0 max-w-5xl\">\n        <div class=\"justify-start cu-textmedia-content cu-prose-first-last\" style=\"flex: 0 0 100%;\">\n            <header class=\"font-light prose-xl cu-pageheader md:prose-2xl cu-component-updated cu-prose-first-last\">\n                                    <h1 class=\"cu-prose-first-last font-semibold !mt-2 mb-4 md:mb-6 relative after:absolute after:h-px after:bottom-0 after:bg-cu-red after:left-px text-3xl md:text-4xl lg:text-5xl lg:leading-[3.5rem] pb-5 after:w-10 text-cu-black-700 not-prose\">\n                        Towards a Cure: Carleton Research Team Working on Stem Cell Therapy to Reverse Type 1 Diabetes\n                    <\/h1>\n                \n                                \n                            <\/header>\n\n                    <\/div>\n\n            <\/div>\n\n    <\/div>\n<\/section>\n\n<p>Carleton\u2019s&nbsp;<a href=\"https:\/\/carleton.ca\/biology\/people\/jenny-bruin\/\">Jenny Bruin<\/a>&nbsp;is part of a team of researchers that has been awarded a 5-year, $3 million grant from the&nbsp;<a href=\"https:\/\/cihr-irsc.gc.ca\/e\/193.html\">Canadian Institutes of Health Research<\/a>&nbsp;(CIHR) and&nbsp;<a href=\"https:\/\/www.jdrf.ca\/\">JDRF Canada<\/a>&nbsp;to develop a novel therapy that transplants insulin-secreting cells derived from stem cells into patients with Type 1 diabetes.<\/p>\n\n\n\n<p>\u201cWe want to replace them with beta cells derived from pluripotent stem cells. Right now, we can take stem cells part way down the path to becoming beta cells&nbsp;<em>in vitro<\/em>. When we transplant these cells into mice, the final stages of maturation occur in the mouse over a period of several months. It works really well, but it is kind of like a black box \u2013 we don\u2019t know what is happening in the time after the cells are transplanted, but before they start producing insulin and responding to glucose.\u201d<\/p>\n\n\n\n<p><a href=\"https:\/\/research.carleton.ca\/story\/towards-a-cure-carleton-research-team-working-on-stem-cell-therapy-to-reverse-type-1-diabetes\/\">more&#8230;<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Carleton\u2019s&nbsp;Jenny Bruin&nbsp;is part of a team of researchers that has been awarded a 5-year, $3 million grant from the&nbsp;Canadian Institutes of Health Research&nbsp;(CIHR) and&nbsp;JDRF Canada&nbsp;to develop a novel therapy that transplants insulin-secreting cells derived from stem cells into patients with Type 1 diabetes. \u201cWe want to replace them with beta cells derived from pluripotent stem [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1536,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-1535","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":{"cu_post_thumbnail":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/posts\/1535","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/comments?post=1535"}],"version-history":[{"count":1,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/posts\/1535\/revisions"}],"predecessor-version":[{"id":1537,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/posts\/1535\/revisions\/1537"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/media\/1536"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/media?parent=1535"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/categories?post=1535"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/carleton.ca\/biochem\/wp-json\/wp\/v2\/tags?post=1535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}