{"id":3345,"date":"2014-01-20T10:25:46","date_gmt":"2014-01-20T15:25:46","guid":{"rendered":"http:\/\/carleton.ca\/biology\/?post_type=cu_event&#038;p=3345"},"modified":"2026-02-23T15:51:58","modified_gmt":"2026-02-23T20:51:58","slug":"dr-martin-holcik","status":"publish","type":"cu_event","link":"https:\/\/carleton.ca\/biology\/event\/dr-martin-holcik\/","title":{"rendered":"Dr. Martin Holcik"},"content":{"rendered":"<header class=\"mb-6 cu-pageheader cu-component-updated md:mb-12\">\n    <h1 class=\"cu-prose-first-last font-semibold !mt-2 mb-4 md:mb-6 text-3xl md:text-4xl lg:text-5xl lg:leading-[3.5rem] relative after:absolute after:h-px after:bottom-0 pb-5 after:w-10 after:bg-cu-red after:left-px\">\n        \n    <\/h1>\n    \n        <\/header>\n\n    \n    \n    \n    \n    <div class=\"cu-buttongroup cu-component-updated flex flex-wrap md:flex-1 gap-3 md:gap-5 justify-start\">\n                                                                        <\/div>\n    \n<p><b>Selective translation: tipping the scales of cancer<\/b><b> <\/b><b><\/b><\/p>\n\n\n\n<p>Dr. Martin Holcik, Apoptosis Research Center and the Molecular Biomedicine Program of the Children&#8217;s Hospital of Eastern Ontario Research Institute, and Department of Pediatrics at the University of Ottawa<\/p>\n\n\n\n<p>Friday, February 14<sup>th<\/sup> \u2013 3:30PM \u2013 CTTC 4440Q<\/p>\n\n\n\n<p><b>Faculty Host: Ashkan Golshani<\/b><b><\/b><\/p>\n\n\n\n<p><b>Cancer \u2022 Apoptosis \u2022 Regulation of Protein Synthesis <\/b><\/p>\n\n\n\n<p><i>Dr. Holcik is interested in the investigation of the regulation of protein synthesis, with specific emphasis on selective mRNA translation during pathophysiological cellular states such as cellular stress, apoptosis and cancer. Regulation of gene expression occurs at multiple levels, including translation. Control at the level of protein synthesis (and\/or translation-coupled mRNA stability) allows cells to respond rapidly to changes in physiological conditions. Indeed, the repression or activation of translation occurs almost instantaneously, unlike regulation at other levels (such as transcription, mRNA processing, or protein modification and turnover) which entail a considerable time lag, and is therefore uniquely suited to provide the cell with plasticity to respond to adverse conditions.<\/i><\/p>\n","protected":false},"author":2,"featured_media":0,"template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"cu_event_type":[],"cu_event_audience":[],"class_list":["post-3345","cu_event","type-cu_event","status-publish","hentry"],"acf":{"cu_event_start_date":"2014-02-14T15:30:00","cu_event_end_date":"2014-02-14T16:30:00","cu_event_location_type":"in-person","cu_event_meeting_address_type":"on-campus","cu_building":"TT","cu_event_meeting_room":"4440Q","cu_event_meeting_address_full":null,"cu_event_virtual_type":"tbd","cu_event_virtual_meeting_link":"","cu_post_thumbnail":false,"cu_event_cost":"","cu_event_registration":"","cu_event_secondary_button":"","cu_event_contact_name":"Ashkan Golshani","cu_event_email":"ashkan.golshani@carleton.ca","cu_event_phone":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/biology\/wp-json\/wp\/v2\/cu_event\/3345","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/biology\/wp-json\/wp\/v2\/cu_event"}],"about":[{"href":"https:\/\/carleton.ca\/biology\/wp-json\/wp\/v2\/types\/cu_event"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/biology\/wp-json\/wp\/v2\/users\/2"}],"version-history":[{"count":0,"href":"https:\/\/carleton.ca\/biology\/wp-json\/wp\/v2\/cu_event\/3345\/revisions"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/biology\/wp-json\/wp\/v2\/media?parent=3345"}],"wp:term":[{"taxonomy":"cu_event_type","embeddable":true,"href":"https:\/\/carleton.ca\/biology\/wp-json\/wp\/v2\/cu_event_type?post=3345"},{"taxonomy":"cu_event_audience","embeddable":true,"href":"https:\/\/carleton.ca\/biology\/wp-json\/wp\/v2\/cu_event_audience?post=3345"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}