{"id":2092,"date":"2011-05-24T13:40:23","date_gmt":"2011-05-24T17:40:23","guid":{"rendered":"http:\/\/carleton.ca\/biology\/"},"modified":"2026-08-11T09:44:22","modified_gmt":"2026-08-11T13:44:22","slug":"alex-wong","status":"publish","type":"cu_people","link":"https:\/\/carleton.ca\/biology\/people\/alex-wong\/","title":{"rendered":"Alex Wong"},"content":{"rendered":"
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Research<\/h2>\n\n\n\n

My lab works broadly in microbial genetics and evolution. Current research topics include the effects of genetic background on evolutionary processes, impacts of co-selection on the evolution of antimicrobial resistance, and genomics-enabled microbial surveillance. Visit our lab website<\/a> to find out more.<\/p>\n\n\n\n

Publications<\/h2>\n\n\n\n

Experimental Evolution<\/em><\/p>\n\n\n\n

Phillips LL, Carrasco A, Weiss J, Liu DY, Linington RG, Wong A. 2026. Mutational Basis of Ceftazidime-Borrelidin A Collateral Sensitivity in Escherichia coli<\/em>. G3: Genes, Genomes and Genetics <\/em>16(5): jkag046.<\/p>\n\n\n\n

Hinz A, Amado A, Kassen R, Bank C, Wong A. 2024. Unpredictability of the fitness effects of antimicrobial resistance mutations across environments in Escherichia coli. Mol Biol Evol <\/em>41: msae086.<\/em><\/p>\n\n\n\n

Filipow N, MallonS, ShewaramaniS, KassenR, Wong A. 2024. The Impact of Genetic Background During Laboratory Evolution of Pseudomonas aeruginosa <\/em>in a Cystic Fibrosis-like Environment. Evolution<\/em> 78: 566-578.<\/p>\n\n\n\n

Surveillance<\/em><\/p>\n\n\n\n

Carroll AC, Hinz A, Hicks AMA, Khov E, Van Bakel T, Doukhanine E, Fralick M, Nott C, Kassen R, Thampi N, A. Hug LA, MacFadden DR, Wong A.2026. Targeted metatranscriptomic detection of viruses from floors for simultaneous evaluation of respiratory disease burden and viral variant identification. mSphere <\/em>11(5): e00086-26.<\/em><\/p>\n\n\n\n

Hodzic-Santor B, Hinz A, Kassen R, Liu J-L, DjambazianH, Lee S, Hicks A, Sjaarda C, Wong H, Sheth PM,Nott C, MacFadden DR, Roy A-M, Ragoussis J, Castellani L, Fralick M, Wong A. 2025. Sequencing and Variant Calling of SARS-CoV-2 from Floor Swabs: A Potential Tool for Identifying Emergent Lineages. Microbial Genomics<\/em> 11(12):001575.<\/p>\n\n\n\n

Bradford LM, Yao L, Anastasiadis C, Cooper AL, Deckert A, Reid-Smith R, Lau C, Diarra MS, Carrillo C, Wong A. 2024. Limit of detection of Salmonella<\/em> ser. Enteritidis using culture-based versus culture-independent diagnostic approaches. Microbiology Spectrum <\/em>12: 12.<\/p>\n\n\n\n

Co-selection<\/em><\/p>\n\n\n\n

Ibrahim A, Au J, Wong A. 2025. The Ionophore Resistance Genes narA <\/em>and narB <\/em>are Geographically Widespread and Linked to Resistance to Medically Important Antibiotics. mSphere<\/em> 0:e00243-25.<\/p>\n\n\n\n

Wong A. 2019. Hidden risk on the farm: Does Agricultural Use of Ionophores Contribute to the Burden of Antimicrobial Resistance? mSphere <\/em>4: e00433-19.<\/p>\n\n\n\n

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