{"id":12982,"date":"2022-11-30T11:56:48","date_gmt":"2022-11-30T16:56:48","guid":{"rendered":"https:\/\/carleton.ca\/biology\/?p=12982"},"modified":"2022-11-30T11:56:48","modified_gmt":"2022-11-30T16:56:48","slug":"biology-seminar-series-dr-rhiannon-peery-december-9th-2022-at-230pm","status":"publish","type":"post","link":"https:\/\/carleton.ca\/biology\/2022\/biology-seminar-series-dr-rhiannon-peery-december-9th-2022-at-230pm\/","title":{"rendered":"Biology Seminar Series: Dr. Rhiannon Peery December 9th 2022 at 2:30pm"},"content":{"rendered":"<p><strong>Title:<\/strong><\/p>\n<p>Explaining differential virulence in strains of\u00a0<em>Cronartium harknessii\u00a0<\/em>through comparative genomics<\/p>\n<p><\/p>\n<p><strong>Abstract:<\/strong><\/p>\n<p><em>Cronartium harknessii<\/em>\u00a0(E. Meinecke), the fugal pathogen that causes western gall rust, has variable rates of susceptibility and infection among\u00a0<em>Pinus<\/em><em>\u00a0<\/em>spp. Recently we used the population structure of\u00a0<em>C. harknessii<\/em><em>\u00a0<\/em>and the host species\u00a0lodgepole pine (<em>Pinus contorta<\/em>\u00a0var.\u00a0<em>latifolia<\/em>\u00a0Engelm.), jack pine (<em>Pinus banksiana<\/em>\u00a0Lamb) and their hybrids along with a factorial study of virulence of\u00a0<em>C. harknessii<\/em>\u00a0lineages to test the hypothesis that there is a coevolutionary relationship between host and pathogen. Our results show differential response to fungal lineages with resilience structure of jack pine &gt; hybrids &gt; lodgepole pine. Additionally, we found that there is correlation between\u00a0<em>C. harknessii<\/em><em>\u00a0<\/em>lineage and host. Together these results support a coevolutionary relationship amongst host and pathogen. However, while our study found structure at microsatellite loci, there were numerous clones removed prior to population genetic analysis and ITS\/IGS sequence differentiation between strains was too low to recover the structure. The lack of structure found in sequence data led to the question: What is different among the strains that is causing differential virulence in hosts? To test the hypothesis that there are structural variants rather than point mutations among strains that are causing differences in virulence we generated the first genomes for\u00a0<em>C. harknessii<\/em>. We produced two near chromosome level assemblies<em>\u00a0<\/em>and re-sequenced 54 additional pooled gall samples from each strain. The eastern and western reference assemblies have 18 and 17 scaffolds, respectively. Preliminary examination of the two reference genomes indicates that there are genomic differences that could account for variations in virulence similar to what is seen in the\u00a0<em>fusarium<\/em>\u00a0rust.<\/p>\n<p><strong>Bio:<\/strong><\/p>\n<p>Dr. Rhiannon Peery received an MSc in 2005 from Central Washington University and a PhD in 2015 from the University of Illinois followed by two postdocs and a research associate position at UAlberta.\u00a0During her career Dr. Peery has worked on a wide variety of systems from conifers, to carrots, and chronic wasting disease and considers all her work as falling under the umbrella of applied computational biology and genomics. Her research\u00a0focuses on the integration of methods from bioinformatics, population genomics, phylogenomics, and landscape ecology applied to questions about forest health.\u00a0Currently\u00a0Dr. Peery\u00a0is the bioinformatician on the TRIA-FoR Genome Canada grant co-lead by Dr. Cullingham.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Title: Explaining differential virulence in strains of\u00a0Cronartium harknessii\u00a0through comparative genomics Abstract: Cronartium harknessii\u00a0(E. Meinecke), the fugal pathogen that causes western gall rust, has variable rates of susceptibility and infection among\u00a0Pinus\u00a0spp. Recently we used the population structure of\u00a0C. harknessii\u00a0and the host species\u00a0lodgepole pine (Pinus contorta\u00a0var.\u00a0latifolia\u00a0Engelm.), jack pine (Pinus banksiana\u00a0Lamb) and their hybrids along with a factorial [&hellip;]<\/p>\n","protected":false},"author":46,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_mi_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Biology Seminar Series: Dr. Rhiannon Peery December 9th 2022 at 2:30pm - Department of 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