{"id":420,"date":"2010-03-19T09:06:07","date_gmt":"2010-03-19T13:06:07","guid":{"rendered":"http:\/\/its-cuthemedev1.carleton.ca\/chemistry\/?page_id=420"},"modified":"2025-08-22T09:38:38","modified_gmt":"2025-08-22T13:38:38","slug":"lai-edward-p-c","status":"publish","type":"cu_people","link":"https:\/\/carleton.ca\/chemistry\/people\/lai-edward-p-c\/","title":{"rendered":"Edward P.C. Lai"},"content":{"rendered":"
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\n \n \n \n <\/h1>\n\n \n <\/header>\n\n\n\n

Lab:<\/strong> 423, 315 SC; ext. 4486
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Research Area: Analytical and bioanalytical chemistry<\/strong><\/p>\n\n\n\n

Specific Topics:<\/strong><\/p>\n\n\n\n

Instrumental analysis of biochemical and environmental samples for public health using capillary electrophoresis, dynamic light scattering, fluorescence spectroscopy, gel permeation chromatography, liquid chromatography, mass spectrometry and 3D microfluidics. New photochemical, electrochemical and optical phenomena are developed into analytical methods for enhanced sensitivity and selectivity:  (a) molecularly imprinted polymers for the selective determination of therapeutic drugs in serum, ochratoxin A in red wine, and estrogenic compounds in wastewater treatment by solid-phase extraction with differential pulsed elution; (b) self-assembled monolayers and electropolymerized thin films for adsorption of toxic metals (Hg2+<\/sup>) and mycotoxins; (c) functionalization of colloidal nanoparticles for removal of endocrine disrupting compounds in environmental water and radioactive nuclides (Pu-238, Sr-90, Y-90,) in urine; (d) detection of nanoparticles in environmental water and air samples; (e) microfluidic prints for testing antimicrobial resistance of bacteria (E. coli<\/em>); (f) DNA binding with inorganic oxide nanomaterial surfaces; (g) interaction of nanoparticles with graphene quantum dots and simulated lung fluid.<\/p>\n\n\n\n

Publications: <\/strong><\/p>\n\n\n\n

 <\/p>\n\n\n\n

(132)      Meissam Noroozifar, Zafar Iqbal and Edward P.C. Lai, 2016, \u201cCE-UV Analysis of Biochemically Active Compounds loading onto Chitosan-coated Magnetic Nanoparticles\u201d, Journal of Research Analytica, 2(3), 1-7.<\/p>\n\n\n\n

(131)      Audrey Murray, Banu \u00d6rmeci and Edward P.C. Lai, 2016, \u201cUse of Sub-micron Sized Resin Particles for Removal of Endocrine Disrupting Compounds and Pharmaceuticals from Water and Wastewater\u201d, Journal of Environmental Science, available online July 25.<\/p>\n\n\n\n

(130)      Edward P.C. Lai, Isa Mohammed, Cheryl MacPhee and Alison R. Schwass, 2016, \u201cSurface Plasmon Resonance Biosensor for Immunoassay of Peanut Allergenic Proteins\u201d, Journal of Research Analytica, 2(1), 5-11.<\/p>\n\n\n\n

(129)      Edward P.C. Lai, Zafar Iqbal and Tyler J. Avis, 2016, Antimicrobial Agents \u2013 Combating Antimicrobial Resistance of Foodborne Microorganisms\u201d, Journal of Food Protection, 79(2), 321-336.<\/p>\n\n\n\n

(128)      Audrey Murray, Banu \u00d6rmeci and Edward P.C. Lai, 2016, \u201cRemoval of Endocrine Disrupting Compounds from Wastewater using Polymer Particles\u201d, Water Science & Technology, 73(1), 176-181.<\/p>\n\n\n\n

(127)     Olaitan Edu and Edward P.C. Lai, 2015, \u201cAirborne Silica and Titanium Dioxide Nanoparticles: Collection with Aqueous Surfactant or Chemical Reagent\u201d, Journal of Nanomaterials & Molecular Nanotechnology, 4:2. doi:10.4172\/2324-8777.1000162<\/p>\n\n\n\n

(126)      Samar Alsudir and Edward P.C. Lai, 2015, \u201cEnhancement of Detection Sensitivity for Colloidal Nanoparticles in Capillary Electrophoresis Analysis\u201d, Journal of Analytical & Bioanalytical Techniques, 6(3), 1000242.<\/p>\n\n\n\n

(125)      Yacoob Shaikh, Edward P.C. Lai, Baki Sadi, Chunsheng Li, 2015, \u201cMagnetic Nanoparticles Hybrid Material Synthesis containing Polymeric 18-Crown-6 Ether: Binding and Detection of Radioactive Strontium\u201d, Nanoscience and Technology: Open Concept, 2(1), 1-5.<\/p>\n\n\n\n

(124)      Noof A. Alenazi, Jeffrey M. Manthorpe and Edward P.C. Lai, 2015, \u201cSelective Extraction of BPA in Milk Analysis by Capillary Electrophoresis using a Chemically Modified Molecularly Imprinted Polymer”, Food Control, 50, 778\u2013783.<\/p>\n\n\n\n

(123)      Zackary Varve, Edward P.C. Lai, Baki Sadi and Chunsheng Li, 2015, \u201cSelective Extraction of 90<\/sup>Sr in Urine using 4\u20194\u201d(5\u201d)Di-tert-butyl Dicyclohexano-18-crown-6 Ether immobilized on Polyacrylamide-coated Magnetic Nanoparticles\u201d, Journal of Radioanalytical and Nuclear Chemistry, 303(1), 1053-1057.<\/p>\n\n\n\n

(122)      Noof Alenazi, Edward P.C. Lai and Jeffrey Manthorpe, 2014, \u201cEnhanced Selectivity of Molecularly Imprinted Polymer towards Target Molecule by Esterification of Non-Specific Binding Sites with Diazomethane\u201d, Journal of Molecular Recognition, 27(12), 755-762.<\/p>\n\n\n\n

(121)      Edward P.C. Lai, Zafar Iqbal and Sherif Nour, 2014, \u201cPolymerization of Vinylpyrrolidone to form a Neutral Coating on Anionic Nanomaterials in Aqueous Suspension for Rapid Sedimentation\u201d, Coatings, 4(2), 340-355.<\/p>\n\n\n\n

(120)      Musharraf Miah, Zafar Iqbal and Edward P.C. Lai, 2014, \u201cA comparative CE-UV binding tests study between polydopamine-coated and polypyrrole-coated magnetic nanoparticles with endocrine disrupting compounds and pharmaceuticals in water\u201d, CLEAN Soil Air Water, 43(2), 173-181.<\/p>\n\n\n\n

(119)      Samar Alsudir and Edward P.C. Lai, 2014, \u201cPolymer Coatings for Sensitive Analysis of Colloidal Silica Nanoparticles in Water\u201d, Colloid and Polymer Science, 292, 1289-1296. DOI: 10.1007\/s00396-014-3184-1.<\/p>\n\n\n\n

(118)      Zafar Iqbal and Edward P.C. Lai, 2013, \u201cInvestigation of Polydopamine Growth on Nanomaterials in Water\u201d, Journal of Nanomaterials and Molecular Nanotechnology, 2(6),  doi: 10.4172\/2324-8777.1000127.<\/p>\n\n\n\n

(117)      Natalie Mesnic, Baki Sadi, Chunsheng Li and Edward Lai, 2013, \u201cApplication of Magnetic Nanoparticles for the Extraction of Radium-226 from Water Samples\u201d, Journal of Radioanalytical and Nuclear Chemistry, 298(3), 1501-1509.<\/p>\n\n\n\n

(116)      Samar Alsudir and Edward P.C. Lai, 2013, \u201cHigh Specificity of Molecularly Imprinted Polymer Particles toward Target Compound in Competitive Environmental Binding\u201d, European Chemical Bulletin, 2(3), 112-118.<\/p>\n\n\n\n

(115)      Xinlong Xia, Edward P.C. Lai and Banu Ormeci, 2013, \u201cDuo-Molecularly Imprinted Polymer-Coated Magnetic Particles for Class-Selective Removal of Endocrine Disrupting Compounds from Aqueous Environment\u201d, Environmental Science & Pollution Research, 20(5), 3331-3339.<\/p>\n\n\n\n

(114)      Mark Pereira and Edward P.C. Lai, 2012, \u201cInteraction of Estrogen-functionalized Quantum Dots with Anti-estrogen Antibodies via Capillary Electrophoresis\u201d, Micro & Nanosystems, 4(4), 320-325.<\/p>\n\n\n\n

(113)      Zafar Iqbal, Edward P.C. Lai and Tyler J. Avis, 2012, \u201cAntimicrobial Effect of Polydopamine Coating on Escherichia coli\u201d, Journal of Materials Chemistry (I.F. = 5.9), 22(40), 21608-21612.<\/p>\n\n\n\n

(112)      Musharraf Miah, Zafar Iqbal and Edward P.C. Lai, 2012, \u201cRapid In-Capillary CE-UV Binding Tests of Endocrine Disrupting Compounds and Pharmaceuticals with Polypyrrole-coated Magnetic Nanoparticles\u201d, Analytical Methods, 4(9), 2866-2878.<\/p>\n\n\n\n

(111)      Xinlong Xia, Edward P.C. Lai and Banu Ormeci, 2012, \u201cUltrasonication Assisted Synthesis of MIP-Encapsulated Magnetic Nanoparticles for Rapid and Selective Removal of 17\u03b2-Estradiol from Aqueous Environment\u201d, Polymer Engineering & Science, 52(8), 1775\u20131783.<\/p>\n\n\n\n

(110)      Zack Varve, Edward P.C. Lai, Chunsheng Li, Baki B. Sadi, and Gary H. Kramer, 2012, \u201cPolymer-coated magnetic nanoparticles for rapid bioassay of 90<\/sup>Sr in human urine samples\u201d, Journal of Radioanalytical and Nuclear Chemistry, 292, 1411-1415.<\/p>\n\n\n\n

(109)      Samar Alsudir, Zafar Iqbal and Edward P.C. Lai, 2012, \u201cRapid CE-UV Binding Tests for Selective Recognition of Bisphenol A by Molecularly Imprinted Polymer Particles\u201d, Electrophoresis, 33(8), 1255-1262.<\/p>\n\n\n\n

(108)      Amy Hrdina, Edward Lai, Chunsheng Li, Baki Sadi and Gary H. Kramer, 2012, \u201cSynthesis of Crown Ether Modified Cation Exchange Polymer Particles for 90<\/sup>Sr Urinalysis\u201d, Reactive and Functional Polymers, 72, 295-302.<\/p>\n\n\n\n

(107)      Zafar Iqbal, Edward P.C. Lai and Tyler J. Avis, 2012, \u201cDevelopment of polymer-modified magnetic nanoparticles and quantum dots for Escherichia coli<\/em> binding test\u201d, Microchimica Acta (I.F. = 3.0), 176(1), 193-200.<\/p>\n\n\n\n

(106)      Edward P. C. Lai, Negar Bahraini, Chunsheng Li, Baki B. Sadi, and Gary H. Kramer, 2012, \u201cCd2+<\/sup>, Cu2+<\/sup>, Pb2+<\/sup>, Sr2+<\/sup> and Y3+<\/sup> Binding Characteristics of 17b-Estradiol Molecularly Imprinted Polymer Particles (Impregnated with Dicyclohexano-18-Crown-6) for Urine Bioassay\u201d, Journal of Applied Polymer Science, 123(1), 12-19.<\/p>\n\n\n\n

(105)      Min Liu, Edward P.C. Lai and Yu Yang, 2012, \u201cRemoval of 17\u03b2-Estradiol by Nylon Filter Membrane: Adsorption Kinetics and Thermodynamics\u201d, International Journal of Research and Reviews in Applied Sciences, 11(1), 67-73.<\/p>\n\n\n\n

(104)      Giao Do, Edward P.C. Lai and Mohammad Hassanzadeh-Khayyat, 2011, \u201cDegradation of Diclofenac by Acid Treatment for Water Purification using Molecularly Imprinted Polymer Particles\u201d, Journal of Advanced Pharmaceutical Research, 2(4), 150-156.<\/p>\n\n\n\n

(103)      Min Liu, Edward P.C. Lai and Yu Yang, 2011, \u201cRemoval of 17\u03b2-Estradiol by Nylon Filter Membrane: Adsorption Mechanism, pH Effect and Temperature Influence\u201d, Proceedings, World Congress on Engineering and Technology (CET 2011, Shanghai, China, October 28-30.<\/p>\n\n\n\n

(102)      Baki B. Sadi, Chunsheng Li, Gary H. Kramer, Cassandra L. Johnson, Queenie Ko and Edward P.C. Lai, 2011, \u201cRapid Determination of 226<\/sup>Ra in Drinking Water Samples Using Dispersive Liquid-Liquid Microextraction Coupled with Liquid Scintillation Counting\u201d, Journal of Radioanalytical and Nuclear Chemistry, 290(2), 415-425.<\/p>\n\n\n\n

(101)      Mohammad Hassanzadeh-Khayyat, Edward P.C. Lai, Kerim Kollu and Banu Ormeci, 2011, \u201cDegradation of Diclofenac in Molecularly Imprinted Polymer Submicron Particles by UV Light Irradiation and HCl Acid Treatment\u201d, Journal of Water Resource and Protection, 3(9), 643-654.<\/p>\n\n\n\n

(100)      Audrey Murray, Banu Ormeci and Edward Lai, 2011, \u201cRemoval of 17b-Estradiol and Chlorination By-products from Water and Wastewater using Non-Imprinted Polymer Particles” Water Science and Technology, 64(6), 1291-1297.<\/p>\n\n\n\n

(99)         Yu Yang and Edward P.C. Lai, 2011, “Optimization of Molecularly Imprinted Polymer Method for Rapid Screening of 17b-Estradiol in Water by Fluorescence Quenching,” International Journal of Analytical Chemistry, Article ID 214747, 8 pages.  doi:10.1155\/2011\/214747.<\/p>\n\n\n\n

(98)        Zafar Iqbal, Samar Alsudir, Musharraf Miah and Edward P.C. Lai, 2011, \u201cRapid CE-UV Binding Tests of Environmentally Hazardous Compounds with Polymer-modified Magnetic Nanoparticles\u201d, Electrophoresis, 32, 1-7.<\/p>\n\n\n\n

(97)        Badruz Zaman, Toya Nath Baral, Zygmunt J. Jakubek, Jianbing Zhang, Edward Lai, Dennis Whitfield and Kui Yu, 2011, “Single-Domain Antibody Bioconjugated Near-IR Quantum Dots for Targeted Cellular Imaging of Pancreatic Cancer”, Journal of Nanoscience and Nanotechnology, 11, 1\u20137.<\/p>\n\n\n\n

(96)        Amy Hrdina, Edward P.C. Lai, Chunsheng Li, Baki Sadi, and Gary Kramer, 2011, \u201cRapid 90<\/sup>Sr Bioassay using Magnetic Cation Exchange Polymer Suspension\u201d, Health Physics Journal, 101(2), 187-195.<\/p>\n\n\n\n

(95)        Negar Bahraini, Edward P.C. Lai, Chunsheng Li, Baki B. Sadi and Gary H. Kramer, 2011, \u201cMolecularly Imprinted Polymers for 90<\/sup>Sr Bioassay\u201d, Health Physics Journal, 101(2), 128-135.<\/p>\n\n\n\n

(94)        Audrey Murray, Banu Ormeci and Edward Lai, 2010, \u201cEvaluation of Non-Imprinted Polymer Nanoparticles for Removal of Endocrine Disrupting Compounds from Surface Water and Wastewater\u201d, Proceedings of WEFTEC 2010, Water Environment Federation, New Orleans, Louisiana, October 2-6, 2010.<\/p>\n\n\n\n

(93)       Jorn C.C. Yu and Edward P.C. Lai, 2010, \u201cMolecularly Imprinted Polymers for Ochratoxin A Extraction and Analysis\u201d, Toxin, 2(6), 1536-1553.<\/p>\n\n\n\n

(92)        Baki Sadi, Chunsheng Li, Negar Bahraini, Edward Lai and Gary H. Kramer, 2010, \u201cSelectivity of 90<\/sup>Sr Urine Bioassay Technique over 241<\/sup>Am, 238\/239<\/sup>Pu, 210<\/sup>Po, 137<\/sup>Cs and 60<\/sup>Co\u201d, Radiation Protection Dosimetry, 141(2), 205-209.<\/p>\n\n\n\n

(91)        Yiyan Li and Edward P.C. Lai, 2010, \u201cExtraction of 17b-Estradiol in Water using Non-imprinted Polymer Submicron Particles in Syringe Filters\u201d, Journal of Environmental Science, 22(11) 1820\u20131825.<\/p>\n\n\n\n

(90)        Yu Yang and Edward P.C. Lai, 2010, \u201cAn Investigation of Porous Structure in Molecularly Imprinted Polymer for Sensor Development:  Non-linear Fluorescence Quenching of 17\u03b2-Estradiol bound inside MIP Submicron Particles by Sodium Nitrite and Methacrylamide\u201d, Journal of Photochemistry and Photobiology A: Chemistry,  213, 123-128.<\/p>\n\n\n\n

(89)        Zack DeMaleki, Edward P.C. Lai and Ewa Dabek-Zlotorzynska, 2010, \u201cCapillary Electrophoresis Characterization of Molecularly Imprinted Polymer Particles in Fast Binding with 17\u03b2-Estradiol\u201d, Journal of Separation Science, 116 (3), 2796-2803.<\/p>\n\n\n\n

(88)        Amy Hrdina, Edward P.C. Lai, Chunsheng Li, Baki Sadi, and Gary Kramer, 2010, \u201cA Comparative Study of Magnetic Transferability of Superparamgnetic Nanoparticles\u201d, Journal of Magnetism and Magnetic Materials, 322, 2622-2627.<\/p>\n\n\n\n

(87)        Baki B. Sadi, Chunsheng Li, Sara Jodayree, Edward P.C. Lai, Vera Kochermin and Gary H. Kramer, 2010, \u201cA Rapid Bioassay Method for the Determination of 90<\/sup>Sr in Human Urine Sample\u201d, Radiation Protection Dosimetry.  140(1), 41-48.<\/p>\n\n\n\n

(86)        Randy Jackson, Ilona Petrickovics, Edward P.C. Lai  and Jorn C.C. Yu, 2010, \u201cMolecularly Imprinted Polymer Stir Bar Sorption Extraction and Electrospray Ionization Tandem Mass Spectrometry for Determination of 2-Aminothiazoline-4-Carboxylic Acid in Forensic Urine Analysis\u201d, Analytical Methods, 2, 552-557.<\/p>\n\n\n\n

(85)        Edward P.C. Lai, Zack DeMaleki and Shuyi Wu, 2010, \u201cCharacterization of Molecularly-Imprinted and Non-Imprinted Polymer Submicron Particles Specifically Tailored for Removal of Trace 17\u03b2-Estradiol in Water Treatment\u201d, Journal of Applied Polymer Science, 116 (3), 1499-1508. (84)        Yu Yang, Edward P.C. Lai and Min Liu, 2010, \u201cSpectroscopic Analysis of Poly (Methacrylic Acid-co<\/em>-Ethylene Glycol Dimethacrylate) Submicron Particles by Fluorescence Emission and Light Scattering upon Binding with 17\u03b2-Estradiol in Water Treatment\u201d, Open Colloid Science Journal, 3(8), 1-8.<\/p>\n\n\n\n

(83)        Chunsheng Li, K. Benkhedda, Zack Varve, Vera Kochemin, Baki B. Sadi, Edward P.C. Lai and Gary H. Kramer, 2009, \u201cFast Methods for 239<\/sup>Pu Faecal Bioassay\u201d, Journal of Analytical Atomic Spectrometry, <\/em>24, 1429\u20131433.<\/em><\/p>\n\n\n\n

(82)        Chunsheng Li, Baki B. Sadi, Gerry Moodie, Joseph N. Daka, Edward P.C. Lai, Gary H. Kramer, 2009, \u201cField Deployable Technique for 90<\/sup>Sr Emergency Bioassay\u201d, Radiation Protection Dosimetry, 136(2), 82-86.<\/p>\n\n\n\n

(81)        Mark Pereira and Edward P.C. Lai, 2008, \u201cCapillary Electrophoresis for the Characterization of Quantum Dots after Non-selective or Selective Bioconjugation with Antibodies for Immunoassay\u201d, Journal of Nanobiotechnology, 6(1):10.  doi: 10.1186\/1477-3155-6-10<\/p>\n\n\n\n

(80)        Yun Wei, Long Qiu, Craig Owen and Edward P.C. Lai, 2007, \u201cEncapsulation of Quantum Dots and Carbon Nanotubes with Polypyrrole in a Syringe Needle for Automated Molecularly Imprinted Solid Phase Pre-concentration of Ochratoxin A in Red Wine Analysis\u201d, Sensing and Instrumentation for Food Quality and Safety, 1, 133-141.<\/p>\n\n\n\n

(79)        Yun Wei, Longhui Qiu, Jorn C.C. Yu and Edward P.C. Lai, 2007, \u201cMolecularly Imprinted Solid Phase Extraction in a Syringe Needle packed with Polypyrrole-encapsulated Carbon Nanotubes for Determination of Ochratoxin A in Red Wine\u201d, Food Science and Technology International, 13, 375-380.<\/p>\n\n\n\n

(78)        Jorn C.C. Yu, Amy Hrdina, Christina Mancini, and Edward P.C. Lai, 2007, \u201cMolecularly Imprinted Polypyrrole Encapsulated Carbon Nanotubes in Stainless Steel Frit for Micro Solid Phase Extraction of Estrogenic Compounds\u201d, Journal of Nanoscience and Nanotechnology, 7(9), 3095-3103.<\/p>\n\n\n\n

(77)        Mark Pereira, Edward P.C. Lai and Bryan Hollebone, 2007, \u201cCharacterization of Quantum Dots Using Capillary Zone Electrophoresis\u201d, Electrophoresis, 28, 2874-2881.<\/p>\n\n\n\n

(76)        Jorn C.C. Yu and Edward P.C. Lai, 2007, “Determination of Ochratoxin A in Red Wines by Multiple Pulsed Elutions from Molecularly Imprinted Polypyrrole\u201d, Food Chemistry, 105, 301-310.<\/p>\n\n\n\n

(75)        Ting Lu, Edward P.C. Lai and Jorn C.C. Yu, 2006, \u201cAnalysis for Flavonoids in Bee Pollens by Capillary Electrophoresis\u201d, Food Science (ISSN 1002-6630), 27(12), 582-587.<\/p>\n\n\n\n

(74)        Ting Lu, Jorn C.C. Yu, Yisu Li, Erika Revesz and Edward P.C. Lai, 2006, \u201cRapid Analysis for Flavonoids in Propolis by Capillary Electrophoresis\u201d, Food Science (ISSN 1002-6630), 27(8), 208-213.<\/p>\n\n\n\n

(73)        Edward P.C. Lai and Sherry Y. Feng, 2006, \u201c<\/strong>Solid Phase Extraction \u2013 Non-aqueous Capillary Electrophoresis for Rapid Determination of Metformin in Human Plasma\u201d, Journal of Chromatography B, 843, 94-99.<\/p>\n\n\n\n

(72)        Jorn C.C. Yu and Edward P.C. Lai, 2006. “Molecularly Imprinted Polypyrrole Modified Carbon Nanotubes on Stainless Steel Frit for Selective Micro Solid Phase Pre-concentration of Ochratoxin A”, Reactive & Functional Polymers, 66, 702-711.<\/p>\n\n\n\n

(71)        Jorn C.C. Yu, Svetla Krushkova, Edward P.C. Lai and Ewa Dabek-Zlotorzynska, 2005, \u201cMolecularly Imprinted Polypyrrole Modified Stainless Steel Frits for Selective Solid Phase Pre-concentration of Ochratoxin A\u201d, Analytical and Bioanalytical Chemistry, 382, 1534-1540.<\/p>\n\n\n\n

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