{"id":3025,"date":"2019-01-15T11:00:02","date_gmt":"2019-01-15T16:00:02","guid":{"rendered":"https:\/\/its-cuthemedev1.carleton.ca\/chemistry\/?page_id=3025"},"modified":"2025-08-18T14:50:36","modified_gmt":"2025-08-18T18:50:36","slug":"sensitive-detection-of-foodborne-pathogenic-bacteria-using-microfluidic-devices","status":"publish","type":"page","link":"https:\/\/carleton.ca\/chemistry\/sensitive-detection-of-foodborne-pathogenic-bacteria-using-microfluidic-devices\/","title":{"rendered":"Sensitive detection of foodborne pathogenic bacteria using microfluidic devices"},"content":{"rendered":"\n<section class=\"w-screen px-6 cu-section cu-section--white ml-offset-center md:px-8 lg:px-14\">\n    <div class=\"space-y-6 cu-max-w-child-5xl  md:space-y-10 cu-prose-first-last\">\n\n            <div class=\"cu-textmedia flex flex-col lg:flex-row mx-auto gap-6 md:gap-10 my-6 md:my-12 first:mt-0 max-w-5xl\">\n        <div class=\"justify-start cu-textmedia-content cu-prose-first-last\" style=\"flex: 0 0 100%;\">\n            <header class=\"font-light prose-xl cu-pageheader md:prose-2xl cu-component-updated cu-prose-first-last\">\n                                    <h1 class=\"cu-prose-first-last font-semibold !mt-2 mb-4 md:mb-6 relative after:absolute after:h-px after:bottom-0 after:bg-cu-red after:left-px text-3xl md:text-4xl lg:text-5xl lg:leading-[3.5rem] pb-5 after:w-10 text-cu-black-700 not-prose\">\n                        Sensitive detection of foodborne pathogenic bacteria using microfluidic devices\n                    <\/h1>\n                \n                                \n                            <\/header>\n\n                    <\/div>\n\n            <\/div>\n\n    <\/div>\n<\/section>\n\n\n\n<section class=\"w-screen px-6 cu-section cu-section--white ml-offset-center md:px-8 lg:px-14\">\n    <div class=\"space-y-6 cu-max-w-child-5xl  md:space-y-10 cu-prose-first-last\">\n\n        \n    <div class=\"grid gap-6 mx-auto my-6 cu-column md:gap-10 md:grid-cols-2 md:my-10 first:mt-0\">\n        \n<div class=\"cu-column-content\">\n    \n\n<p><strong>Speaker<\/strong>: Professor Xudong Cao, Ottawa-Carleton Institute of Biomedical Engineering, University of Ottawa<\/p>\n\n\n\n<p><strong>Title<\/strong>: Sensitive detection of foodborne pathogenic bacteria using microfluidic devices<\/p>\n\n\n\n<p><strong>Date, Time and Place:<\/strong> Friday, Jan. 25, 2019, TB 202<\/p>\n\n\n<\/div>\n\n\n<div class=\"cu-column-content\">\n    \n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"160\" height=\"212\" src=\"https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/profile-160x212.jpg\" alt=\"Xudong Cao profile picture\" class=\"wp-image-3026\" srcset=\"https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/profile-160x212.jpg 160w, https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/profile-240x317.jpg 240w, https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/profile-360x476.jpg 360w, https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/profile.jpg 363w\" sizes=\"auto, (max-width: 160px) 100vw, 160px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n<\/div>\n\n\n    <\/div>\n\n\n    <\/div>\n<\/section>\n\n\n\n<p>Identification and quantification of foodborne pathogens are becoming increasinglyimportant to public health and food safety since the majority of foodborne illnesses and deaths are caused by pathogenic bacteria. Conventional methods for foodborne pathogen detection are time-consuming and laborious due to the requirement of a series of processes including cell enrichment, isolation and morphological identification. Therefore, the demand for rapid, sensitive, inexpensive and convenient approaches to detect foodborne pathogenic bacteria has emerged in recent years. Among those new approaches, microfluidic chip-based detection has generated growing interests because of their miniaturized size, improved sensitivity and reduced detection time. To this end, our research group have been working on strategies to enhance detection signals using aptamers to effectively capture detection targets and subsequently enhance detections by rolling circle amplifications (RCA). In this seminar, I will talk about our recent efforts to surface modify microfluidic channels in order to improve target capturing efficiencies and discuss our approaches to intensify signals for sensitive detections.<\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"980\" height=\"663\" src=\"https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/chem.jpg\" alt=\"chemistry diagrams\" class=\"wp-image-3027\" srcset=\"https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/chem.jpg 980w, https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/chem-160x108.jpg 160w, https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/chem-240x162.jpg 240w, https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/chem-768x520.jpg 768w, https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/chem-400x271.jpg 400w, https:\/\/carleton.ca\/chemistry\/wp-content\/uploads\/sites\/138\/chem-360x244.jpg 360w\" sizes=\"auto, (max-width: 980px) 100vw, 980px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Schematic drawing of the microfluidic microchannel detection system with RCA signal enhancement<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Identification and quantification of foodborne pathogens are becoming increasinglyimportant to public health and food safety since the majority of foodborne illnesses and deaths are caused by pathogenic bacteria. Conventional methods for foodborne pathogen detection are time-consuming and laborious due to the requirement of a series of processes including cell enrichment, isolation and morphological identification. Therefore, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_cu_dining_location_slug":"","footnotes":"","_links_to":"","_links_to_target":""},"cu_page_type":[],"class_list":["post-3025","page","type-page","status-publish","hentry"],"acf":{"cu_post_thumbnail":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/pages\/3025","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/comments?post=3025"}],"version-history":[{"count":4,"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/pages\/3025\/revisions"}],"predecessor-version":[{"id":5306,"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/pages\/3025\/revisions\/5306"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/media?parent=3025"}],"wp:term":[{"taxonomy":"cu_page_type","embeddable":true,"href":"https:\/\/carleton.ca\/chemistry\/wp-json\/wp\/v2\/cu_page_type?post=3025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}