The Transformational Research: Canada program funds transformative, novel, high-risk, high-reward translational research projects.

Goal: To provide funding for translational research that will accelerate the development of therapeutics for neurodegenerative diseases of aging.


Applicant Eligibility: Eligible Principal Applicants must be researchers working in Canada at least 30% of the time at or above the level of Assistant Professor or equivalent, and be affiliated with a Canada Revenue Agency-qualified donee institution located in Canada. Co-Applicants/Collaborators must be at the post-doctoral level or above and can be working outside Canada.

Applicants may appear in any role on any number of projects.

Project Eligibility: Projects must meet the following conditions to be eligible:

  • Be translational research (excluding clinical trials and clinical trial sub-studies) that accelerates the development of therapeutics for neurodegenerative diseases of aging.
    • Clinical trials and clinical trial sub-studies should be submitted to the Early-Phase Clinical Trials or Rapid Response programs; however other translational research using humans or human samples/data is in scope.
  • Be the development of a therapeutic and/or tool and/or select complementary approaches (Please refer to the AD/PD Program Details for more information on complementary approaches that are in scope)

The project structure (i.e. the frequency and detail of the go/no go milestones) and the quality of the preliminary data should commensurate with the size of budget. For example: A project requesting $1,500,000 for 3 years should have strong preliminary data and multiple go/no-go milestones, whereas a project requesting $200,000 could have minimal preliminary data and less frequent milestones.

Please refer to What We Fund for Institute definitions of neurodegenerative diseases of aging, translational research, therapeutic, tool, and complementary approaches.

Funding Available

A maximum of $1,500,000 over up to 3 years per project. Encouraging applications at all funding levels from $200,000 to $1,500,000, without need for preliminary data.

Useful Links

  • For further details about funding categories, eligibility criteria and deadlines, click here.


Internal Review Please contact your Research Facilitator
Letter of Intent Parkinson’s and Related Diseases: March 13, 2019 at 2:00pm EDT

Alzheimer’s and Related Diseases: April 1, 2019 at 2:00pm EDT

cuResearch Approval Form Parkinson’s and Related Diseases: July 9, 2019

Alzheimer’s and Related Diseases: July 23, 2019

Submission to Sponsor Parkinson’s and Related Diseases: July 16, 2019 at 2:00pm EDT

Alzheimer’s and Related Diseases: July 30, 2019 at 2:00pm EDT

Submitting Your Application

  • Applications must be submitted via cuResearch, through which Departmental and Associate Dean’s approval must be provided to complete the online application process.
  • More information on cuResearch can be found here.

Internal Contacts

If you would like assistance with proposal development and/or a substantive review of your proposal, please contact the appropriate Research Facilitator.