{"id":2071,"date":"2025-05-09T10:12:00","date_gmt":"2025-05-09T14:12:00","guid":{"rendered":"https:\/\/carleton.ca\/dsaai\/?p=2071"},"modified":"2026-05-20T10:09:48","modified_gmt":"2026-05-20T14:09:48","slug":"carleton-dsaai-phd-elmira-amoeei-uses-ai-to-personalize-transplant-drug-dosing","status":"publish","type":"post","link":"https:\/\/carleton.ca\/dsaai\/2025\/carleton-dsaai-phd-elmira-amoeei-uses-ai-to-personalize-transplant-drug-dosing\/","title":{"rendered":"Carleton DSAAI PhD Student Elmira Amoeei Uses AI to Personalize Transplant Drug Dosing"},"content":{"rendered":"\n<section class=\"w-screen px-6 cu-section cu-section--white ml-offset-center md:px-8 lg:px-14\">\n    <div class=\"space-y-6 cu-max-w-child-5xl  md:space-y-10 cu-prose-first-last\">\n\n            <div class=\"cu-textmedia flex flex-col lg:flex-row mx-auto gap-6 md:gap-10 my-6 md:my-12 first:mt-0 max-w-5xl\">\n        <div class=\"justify-start cu-textmedia-content cu-prose-first-last\" style=\"flex: 0 0 100%;\">\n            <header class=\"font-light prose-xl cu-pageheader md:prose-2xl cu-component-updated cu-prose-first-last\">\n                                    <h1 class=\"cu-prose-first-last font-semibold !mt-2 mb-4 md:mb-6 relative after:absolute after:h-px after:bottom-0 after:bg-cu-red after:left-px text-3xl md:text-4xl lg:text-5xl lg:leading-[3.5rem] pb-5 after:w-10 text-cu-black-700 not-prose\">\n                        Carleton DSAAI PhD Student Elmira Amoeei Uses AI to Personalize Transplant Drug Dosing\n                    <\/h1>\n                \n                                \n                            <\/header>\n\n                    <\/div>\n\n            <\/div>\n\n    <\/div>\n<\/section>\n\n<p>Following organ transplant surgery, patients may be prescribed a strong immunosuppressant drug called tacrolimus. The blood levels of the medication can be highly variable among patients which can lead to increased risks.<\/p>\n\n\n\n<div id=\"attachment_95818\" class=\"wp-caption alignright\">\n<figure><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-95818\" src=\"https:\/\/newsroom.carleton.ca\/wp-content\/uploads\/ai-research-new-ground-800x800-1.jpg\" sizes=\"auto, (max-width: 350px) 100vw, 350px\" srcset=\"https:\/\/newsroom.carleton.ca\/wp-content\/uploads\/ai-research-new-ground-800x800-1.jpg 800w, https:\/\/newsroom.carleton.ca\/wp-content\/uploads\/ai-research-new-ground-800x800-1-400x400.jpg 400w, https:\/\/newsroom.carleton.ca\/wp-content\/uploads\/ai-research-new-ground-800x800-1-300x300.jpg 300w, https:\/\/newsroom.carleton.ca\/wp-content\/uploads\/ai-research-new-ground-800x800-1-768x768.jpg 768w, https:\/\/newsroom.carleton.ca\/wp-content\/uploads\/ai-research-new-ground-800x800-1-150x150.jpg 150w, https:\/\/newsroom.carleton.ca\/wp-content\/uploads\/ai-research-new-ground-800x800-1-700x700.jpg 700w, https:\/\/newsroom.carleton.ca\/wp-content\/uploads\/ai-research-new-ground-800x800-1-200x200.jpg 200w\" alt=\"A headshot of a woman with long dark hair, wearing a jacket and a hoodie.\" width=\"350\" height=\"350\"><\/figure><p><\/p>\n<p class=\"wp-caption-text\">Elmira Amooei<\/p>\n<\/div>\n\n\n\n<p>Data Science, Analytics, and Artificial Intelligence (DSAAI) PhD student Elmira Amooei is developing AI-based models to personalize the dosing of the drug.<\/p>\n\n\n<div class=\"not-prose cu-quote cu-component-spacing\">\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u201cCurrently, dosing decisions are made based on trial-and-error and generalized guidelines, which do not capture the individual variations in patients and often result in increasing organ rejection or toxicity risks,\u201d says Amooei.<\/p>\n<\/blockquote>\n<\/div>\n\n\n<p>By leveraging AI methods, including machine learning and reinforcement learning techniques, the research team is developing models to predict an individual\u2019s drug response to optimize dosing.<\/p>\n\n\n\n<p>\u201cUsing AI to personalize drug dosing can enhance patient safety and treatment effectiveness,\u201d says Amooei. \u201cThis field of research can potentially serve as a foundation for similar personalized dosing practices.\u201d<\/p>\n\n\n\n<p><em>&#8211; Story by Elizabeth Kane. <a href=\"https:\/\/newsroom.carleton.ca\/story\/carleton-breaking-ground-ai-research\/\" target=\"_blank\" rel=\"noopener\">Read<\/a> about the cutting-edge advancements in AI and machine learning being made by other Carleton graduate students.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Following organ transplant surgery, patients may be prescribed a strong immunosuppressant drug called tacrolimus. The blood levels of the medication can be highly variable among patients which can lead to increased risks. Elmira Amooei Data Science, Analytics, and Artificial Intelligence (DSAAI) PhD student Elmira Amooei is developing AI-based models to personalize the dosing of the [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":2072,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-2071","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":{"cu_post_thumbnail":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/posts\/2071","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/comments?post=2071"}],"version-history":[{"count":3,"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/posts\/2071\/revisions"}],"predecessor-version":[{"id":2193,"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/posts\/2071\/revisions\/2193"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/media\/2072"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/media?parent=2071"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/categories?post=2071"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/carleton.ca\/dsaai\/wp-json\/wp\/v2\/tags?post=2071"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}