{"id":135,"date":"2017-04-03T15:35:45","date_gmt":"2017-04-03T19:35:45","guid":{"rendered":"https:\/\/carleton.ca\/eme\/?page_id=135"},"modified":"2025-07-09T13:54:53","modified_gmt":"2025-07-09T17:54:53","slug":"publications","status":"publish","type":"page","link":"https:\/\/carleton.ca\/eme\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n
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\n Publications\n <\/h1>\n \n \n <\/header>\n\n <\/div>\n\n <\/div>\n\n <\/div>\n<\/section>\n\n\n\n

Selected Publications<\/h2>\n\n\n\n

Antibiotic resistance – Evolution and genomics<\/h3>\n\n\n\n

Hinz A<\/u>, Amado A, Kassen R, Bank C, Wong A. 2024. Unpredictability of the fitness effects of antimicrobial resistance mutations across environments in Escherichia coli. Mol Biol Evol <\/em>41: msae086. <\/em>View here<\/a><\/p>\n\n\n\n

Ibrahim A<\/u>, Bradford L<\/u>, Bult\u00e9 G, Wong A. 2024. Draft Genomes of Meropenem Resistant Pseudomonads<\/em> from the Cloacae of Turtles in Lake Opinicon, Canada. Microbial Resource Announcements <\/em>13. View here<\/a><\/p>\n\n\n\n

Cooper AL<\/u>, Carter C, McLeod H, Sritharan P, Wright M, Koziol AG, Tamber S, Wong A, Carrillo CD, and Blais BW. 2021. Detection of carbapenem-resistance genes in bacteria isolated from wastewater in Ontario. FACETS<\/i>. View here<\/a><\/p>\n\n\n\n

Clarke L<\/u>, Pelin A, Phan M, Wong A. 2020. The effect of environmental heterogeneity on the fitness of antibiotic resistance mutations in Escherichia coli. Evolutionary Ecology.<\/em> View here<\/a><\/p>\n\n\n\n

Bhatnagar K<\/u>, Hinz A<\/u>, Kohlman M<\/u>, Wong A. 2020. An sRNA screen for reversal of quinolone resistance in Escherichia coli. G3: Genes, Genomes, Genetics 10: 79-88. View here<\/a><\/p>\n\n\n\n

Cooper AL<\/u>, Low AJ, Koziol AG, Thomas MC, Leclair D, Tamber S, Wong A, Blais BW, Carrillo CD. 2020. Systematic Evaluation of Whole Genome Sequence-Based Predictions of Salmonella<\/em> Serotype and Antimicrobial Resistance. Frontiers in Microbiology<\/em> 11: 549. View here<\/a><\/p>\n\n\n\n

Bhatnagar K<\/u>, Wong A. 2019. The mutational landscape of quinolone resistance in Escherichia coli. PLoS One<\/em> 14: e0224650. View here<\/a><\/p>\n\n\n\n

Wong A. 2019. Hidden risk on the farm: Does Agricultural Use of Ionophores Contribute to the Burden of Antimicrobial Resistance? mSphere<\/em> 4: e00433-19. View here<\/a><\/p>\n\n\n\n

Basra P<\/u>, Alsaadi A<\/u>, Bernal-Astrain G<\/u>, O’Sullivan ML<\/u>, Hazlett B<\/u>, Clarke LM<\/u>, Schoenrock A, Pitre S, Wong A. 2018. Fitness tradeoffs of antibiotic resistance in extra-intestinal pathogenic Escherichia coli<\/em>. Genome Biology and Evolution<\/em> 10: 667-679. View here<\/a><\/p>\n\n\n\n

Wong A. 2017. Epistatic interactions of antimicrobial resistance mutations. Frontiers in Microbiology <\/em>8: 246. View here<\/a><\/p>\n\n\n\n

Pathogen Detection and Surveillance<\/h3>\n\n\n\n

Bradford LM<\/u>, Yao L<\/u>, Anastasiadis C, Cooper AL, Deckert A, Reid-Smith R, Lau C, Diarra MS, Carrillo C, Wong A. 2024. Limit of detection of Salmonella<\/em> ser. Enteritidis using culture-based versus culture-independent diagnostic approaches. Microbiology Spectrum <\/em>12: 12. View here<\/a><\/p>\n\n\n\n

Bradford <\/u>LM, Carrillo CD, Wong A. 2024. Managing false positives during detection of pathogen sequences in shotgun metagenomics datasets. BMC Bioinformatics <\/em>25: 372. View here<\/a><\/p>\n\n\n\n

Cooper A, Low A, Wong A, Tamber S, Blais BW, Carrillo CD. 2024. Modeling the Limits of Detection for Antimicrobial Resistance Genes in Agri-Food Samples: A Comparative Analysis of Bioinformatics Tools. BMC Microbiology <\/em>24: 31. View here<\/a><\/p>\n\n\n\n

Fralick M, Nott C, Moggridge J, Castellani L, Raudanskis A, Guttman DS, Hinz A<\/u>, Thampi N, Wong A, Manuel D, McGeer A, Doukhanine E, Mejbel H, Zanichelli V, Burella M, Donaldson S, Wang PW, Kassen R, MacFadden D. 2023. Detection of Covid-19 Outbreaks Using Built Environment Testing for SARS-CoV-2. NEJM Evidence 2. <\/em>View here<\/a><\/p>\n\n\n\n

Hinz A<\/u>, Xing LY, Doukhanine E, Hug LA, Kassen R, Ormeci B, Kibbee RJ, Wong A, MacFadden D, Nott C. 2022. SARS-CoV-2 Detection from the Built Environment and Wastewater and Its Use for Hospital Surveillance. FACETS. <\/em>View here<\/a><\/p>\n\n\n\n

Policy<\/h3>\n\n\n\n

Wong A, Hinz A<\/u>, Mac-Seing M, Carabin H, Zarowsky C. 2021. The role of the environment within the One Health approach: The case of infectious diseases. Policy brief<\/a>.<\/p>\n\n\n\n

Ruckert A, Farfard P, Hindmarch S, Morris A, Packer C, Patrick D, Weese S, Wilson K, Wong A, and Labont\u00e9 R. 2020. Governing Antimicrobial Resistance: A Narrative Review of Global Governance Mechanisms. Journal of Public Health Policy<\/em>. View here<\/a><\/p>\n\n\n\n

Experimental evolution<\/h3>\n\n\n\n

Filipow N<\/u>, Mallon S, Shewaramani S, Kassen R, Wong A. 2024. The Impact of Genetic Background During Laboratory Evolution of Pseudomonas aeruginosa <\/em>in a Cystic Fibrosis-like Environment. Evolution<\/em> 78: 566-578. View here<\/a><\/p>\n\n\n\n

Wong A and Seguin K<\/u>. 2015. Effects of genotype on rates of substitution during experimental evolution.  Evolution <\/em>69:1772-85. View here<\/a><\/p>\n\n\n\n

Pathogen comparative genomics<\/h3>\n\n\n\n

Mattrasingh D<\/u>, Hinz A<\/u>, Phillips L<\/u>, Carroll AC<\/u>, and Wong A. 2021. Hybrid Nanopore-Illumina assemblies for five extra-intestinal pathogenic Escherichia coli<\/em> isolates. Microb Resour Announc <\/em>10: e01027-20. View here<\/a><\/p>\n\n\n\n

Huus KE, Joseph J, Zhang L, Wong A, Aaron SD, Mah T-F, Sad S. 2016. Clinical isolates of Pseudomonas aeruginosa from chronically infected cystic fibrosis patients fail to activate the inflammasome during both stable infection and pulmonary exacerbation. J Immunol<\/em> 196: 3097-108. View here<\/a><\/p>\n\n\n\n

Other<\/h3>\n\n\n\n

Shukri A<\/u>, Carroll A<\/u>, Collins R, Charih F, Wong A, Biggar KK. 2024. Systematic in vitro optimization of antimicrobial peptides against Escherichia coli<\/em>. JAC Antimicrob Resist <\/em>6: dlae096. View here<\/a><\/p>\n\n\n\n

Romero J, Islam Md. T, Taylor R, Grayson C<\/u>, Schoenrock A, Wong A. 2022. High-throughput design of bacterial antisense RNAs using CAREng. Bioinformatics Advances <\/em>2: vbac069. View here<\/a><\/p>\n\n\n\n

Diaz S<\/u>, LeBlanc DP, Gagne R, Behan NA, Wong A, Marchetti F, MacFarlane AJ. 2021. Folate Intake Alters Mutation Frequency and Profiles in a Tissue- and Dose-Specific Manner in MutaMouse Male Mice. Journal of Nutrition <\/em>151: 800. View here<\/a><\/p>\n\n\n\n

Page R, Wong A, Arbuckle TE, MacFarlane AJ. 2019. The MTHFR 677C>T polymorphism is associated with unmetabolized folic acid in breast milk in a cohort of Canadian women. American Journal of Clinical Nutrition<\/em> 110: 401-409. View here<\/a><\/p>\n\n\n\n

Burnside D, Schoenrock A, Moteshareie H, Hooshyar M, Samanfar B, Basra P<\/u>, Hajikarimloo M, Dick K, Barnes B, Kazmirchuk T, Jessulat M, Pitre S, Babu M, Green JR, Wong A, Dehne D, Biggar KK, Golshani A. 2019. In silico <\/em>engineering of synthetic binding proteins from random amino acid sequences. iScience<\/em> 11: 375-387. View here<\/a><\/p>\n\n\n\n

 <\/p>\n\n\n\n

Sexual selection and seminal fluid proteins (from the distant past)<\/h3>\n\n\n\n

Wong A. 2014. Covariance between testes size and substitution rates in primates. Molecular Biology and Evolution<\/em> 31: 1432-1436. View here<\/a><\/p>\n\n\n\n

Wong A, Rundle H. 2013. Natural selection on the Drosophila <\/em>seminal fluid protein Acp62F. Ecology and Evolution <\/em>3: 1942-1950. View here<\/a><\/p>\n\n\n\n

Wong A. 2010. Testing the effects of mating system variation on rates of molecular evolution in primates. Evolution <\/em>64: 2779-85. View here<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Selected Publications Antibiotic resistance – Evolution and genomics Hinz A, Amado A, Kassen R, Bank C, Wong A. 2024. Unpredictability of the fitness effects of antimicrobial resistance mutations across environments in Escherichia coli. Mol Biol Evol 41: msae086. View here Ibrahim A, Bradford L, Bult\u00e9 G, Wong A. 2024. Draft Genomes of Meropenem Resistant Pseudomonads […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_cu_dining_location_slug":"","footnotes":"","_links_to":"","_links_to_target":""},"cu_page_type":[],"class_list":["post-135","page","type-page","status-publish","hentry"],"acf":{"cu_post_thumbnail":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/pages\/135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/comments?post=135"}],"version-history":[{"count":4,"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/pages\/135\/revisions"}],"predecessor-version":[{"id":500,"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/pages\/135\/revisions\/500"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/media?parent=135"}],"wp:term":[{"taxonomy":"cu_page_type","embeddable":true,"href":"https:\/\/carleton.ca\/eme\/wp-json\/wp\/v2\/cu_page_type?post=135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}