{"id":6203,"date":"2026-11-12T09:02:40","date_gmt":"2026-11-12T14:02:40","guid":{"rendered":"https:\/\/carleton.ca\/healthsciences\/?post_type=cu_people&#038;p=6203"},"modified":"2026-11-12T09:04:16","modified_gmt":"2026-11-12T14:04:16","slug":"leila-mostaco-guidolin","status":"publish","type":"cu_people","link":"https:\/\/carleton.ca\/healthsciences\/people\/leila-mostaco-guidolin\/","title":{"rendered":"Leila Mosta\u00e7o-Guidolin"},"content":{"rendered":"<header class=\"mb-6 cu-pageheader cu-component-updated md:mb-12\">\n    <h1 class=\"cu-prose-first-last font-semibold !mt-2 mb-4 md:mb-6 text-3xl md:text-4xl lg:text-5xl lg:leading-[3.5rem] relative after:absolute after:h-px after:bottom-0 pb-5 after:w-10 after:bg-cu-red after:left-px\">\n                    \n             \n                \n            <\/h1>\n\n    \n    <\/header>\n\n\n\n\n\n<h2 id=\"primary-field-of-specialization\" class=\"wp-block-heading\">Primary Field of Specialization<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Biomedical Imaging, Biomaterials, and Tissue Engineering<\/p>\n\n\n\n<h2 id=\"research-interests\" class=\"wp-block-heading\"><strong>Research Interests<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">My research focuses on understanding how biological tissues remodel in health, aging, and disease. By combining advanced optical imaging, image analysis, and biomaterials engineering, my team investigates how the extracellular matrix (ECM), the structural scaffold surrounding cells, changes during chronic diseases such as asthma, fibrosis, cancer, and cardiovascular disease. We develop and apply label-free imaging techniques, including multiphoton microscopy, second harmonic generation (SHG), and Raman microspectroscopy, to quantify tissue architecture and uncover structure-function relationships that may serve as new biomarkers or therapeutic targets.<\/p>\n\n\n\n<h2 id=\"selected-publications\" class=\"wp-block-heading\"><strong>Selected Publications<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Mosta\u00e7o-Guidolin LB, et al. <em>Collagen morphology and texture analysis: from statistics to classification<\/em>. Scientific Reports. 2013;3:2190.<\/li>\n\n\n\n<li>Mosta\u00e7o-Guidolin LB, Osei ET, Ullah J, et al. <em>Defective fibrillar collagen organization by fibroblasts contributes to airway remodeling in asthma<\/em>. American Journal of Respiratory and Critical Care Medicine. 2019;200(4):431\u2013443.<\/li>\n\n\n\n<li>Osei ET, Mosta\u00e7o-Guidolin LB, et al. <em>Epithelial\u2013fibroblast communication and extracellular matrix remodeling in chronic airway disease<\/em>. Frontiers in Physiology. 2020.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">Up to date list can be found here: <a href=\"https:\/\/scholar.google.com\/citations?user=3y7q_scAAAAJ&amp;hl=en&amp;authuser=1\">https:\/\/scholar.google.com\/citations?user=3y7q_scAAAAJ&amp;hl=en&amp;authuser=1<\/a><\/p>\n\n\n\n<section class=\"w-screen px-6 cu-section cu-section--white ml-offset-center md:px-8 lg:px-14\">\n    <div class=\"space-y-6 cu-max-w-child-5xl  md:space-y-10 cu-prose-first-last\">\n\n        \n    \n    <dl class=\"cu-description cu-component-updated\">\n        \n    <div class=\"grid pt-4 pb-3 border-b accordion border-cu-black-100 md:pt-6 md:pb-5 first:border-t\">\n        <dt class=\"font-semibold not-prose\">\n            <button class=\"flex items-center justify-between w-full text-left accordion__button\" aria-expanded=\"false\" aria-controls=\"accordion-faculty-fun-fact\">\n                <span class=\"flex-1 ml-auto text-left break-words whitespace-normal cu-icon\">\n                    Faculty Fun fact\n                <\/span>\n                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewbox=\"0 0 24 24\" stroke-width=\"1.5\" stroke=\"currentColor\" aria-hidden=\"true\" data-slot=\"icon\" class=\"w-5 h-5 ml-auto transition-transform rotate-0 accordion__icon text-cu-black-500\">\n                    <path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M8.25 4.5l7.5 7.5-7.5 7.5\"><\/path>\n                <\/svg>\n            <\/button>\n        <\/dt>\n        <dd class=\"p-0 mt-0 cu-prose cu-prose-first-last accordion__content md:p-0 md:mt-0\" hidden=\"\" id=\"accordion-faculty-fun-fact\">\n            \n\n<p class=\"wp-block-paragraph\">Outside the lab, I enjoy sports and have a particular appreciation for challenges that require long-term strategy and persistence, qualities that turn out to be surprisingly useful in scientific research as well.<\/p>\n\n\n        <\/dd>\n    <\/div>\n\n\n    <\/dl>\n\n\n    <\/div>\n<\/section>\n","protected":false},"author":606,"featured_media":6204,"template":"","meta":{"_acf_changed":false,"cu_people_first_name":"Leila","cu_people_last_name":"Mosta\u00e7o-Guidolin","cu_people_initials":"LM","footnotes":"","_links_to":"","_links_to_target":""},"cu_people_type":[7],"cu_people_expertise":[],"class_list":["post-6203","cu_people","type-cu_people","status-publish","has-post-thumbnail","hentry","cu_people_type-cross-appointed-faculty"],"acf":{"cu_people_job_title":"Associate Professor","cu_people_degree":"PhD in Biomedical Engineering (University of Manitoba), MSc (University of S\u00e3o Paulo, Brazil), BSc (University of S\u00e3o Paulo, Brazil )","cu_building":"","cu_people_office_num":"","cu_people_pronoun":"","cu_people_designation":"","cu_people_email":"LeilaGuidolin@cunet.carleton.ca","cu_people_phone":"","cu_people_phone_ext":"","cu_people_linkedin":"","cu_people_bluesky":"","cu_people_twitter":"","cu_people_instagram":"","cu_people_facebook":"","cu_people_website":"https:\/\/www.teb-lab.com","cu_people_orcid":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/cu_people\/6203","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/cu_people"}],"about":[{"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/types\/cu_people"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/users\/606"}],"version-history":[{"count":3,"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/cu_people\/6203\/revisions"}],"predecessor-version":[{"id":6207,"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/cu_people\/6203\/revisions\/6207"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/media\/6204"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/media?parent=6203"}],"wp:term":[{"taxonomy":"cu_people_type","embeddable":true,"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/cu_people_type?post=6203"},{"taxonomy":"cu_people_expertise","embeddable":true,"href":"https:\/\/carleton.ca\/healthsciences\/wp-json\/wp\/v2\/cu_people_expertise?post=6203"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}