{"id":19,"date":"2020-03-19T10:23:04","date_gmt":"2020-03-19T14:23:04","guid":{"rendered":"https:\/\/carleton.ca\/mostacoguidolin\/?page_id=19"},"modified":"2023-02-26T13:46:15","modified_gmt":"2023-02-26T18:46:15","slug":"research","status":"publish","type":"page","link":"https:\/\/carleton.ca\/mostacoguidolin\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<h2>Research Overview<\/h2>\n<p><span style=\"font-weight: 400;\">The main research areas of our group include the characterization of biomaterials, tissues and cells. We want to understand extracellular matrix remodelling and develop in vitro 3D tissue models to understand fundamental mechanisms of diseases. We rely on microscopy and spectroscopy to gather information about the tissue structure at the same time we develop image analysis strategies. The tools we develop are useful in answering relevant biological questions related to the assessment of tissue function during normal and pathological conditions as well as in response to treatments.<\/span><\/p>\n<h3><b>Research Interests<\/b><\/h3>\n<ul>\n<li><span style=\"font-weight: 400;\"> \u00a0 \u00a0 \u00a0 <\/span><span style=\"font-weight: 400;\">Optical microscopy &amp; spectroscopy<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0 \u00a0 \u00a0 <\/span><span style=\"font-weight: 400;\">Extracellular matrix remodelling &amp; fibrosis<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0 \u00a0 \u00a0 <\/span><span style=\"font-weight: 400;\">3D-bioprinting and biomaterials<\/span><\/li>\n<li><span style=\"font-weight: 400;\">\u00a0 \u00a0 \u00a0 \u00a0Digital i<\/span><span style=\"font-weight: 400;\">mage analysis (focus on microscopy and histopathology)<\/span><\/li>\n<\/ul>\n<p>If you are interested in learning more about the research done at <a href=\"https:\/\/carleton.ca\/mostacoguidolin\/research\/hub\/\">Tissue Engineering and BioImaging <\/a><a href=\"https:\/\/carleton.ca\/mostacoguidolin\/research\/hub\/\">Lab<\/a>, please contact me!<\/p>\n<section class=\"content-wrapper content-wrapper--shortcode\"><div class=\"u-post-reload\"><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2024\/tunde-and-natasha-awarded-external-scholarships\/\"><p class=\"news__date news__date--archive\">Monday, June 3, 2024<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">T\u00fcnde and Natasha awarded external scholarships<\/h3><p class=\"news__excerpt news__excerpt--archive\">Two graduate students from our team were awarded prestigious scholarships! T\u00fcnde Lapohos received the Ontario Graduate Scholarship (OGS) in 2024\/25. T\u00fcnde is working on the development of in vitro tissue models to track how cellular responses might be affected by different biomaterials and design strategies. Natasha Kunchur was awarded a CIHR... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2024\/dr-mostaco-guidolin-secures-a-cihr-project-grant\/\"><p class=\"news__date news__date--archive\">Sunday, June 2, 2024<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Dr. Mosta\u00e7o-Guidolin secures a CIHR Project Grant<\/h3><p class=\"news__excerpt news__excerpt--archive\">With a success rate of around 15% and in close collaboration with Dr. Edana Cassol from the department of Health Sciences, (and co-Applicant in the proposal), Dr. Mosta\u00e7o-Guidolin was awarded a 5-year CIHR Project Grant Mapping ECM Remodelling in Asthma Using Multimodal Imaging and Physiologically-Relevant Tissue Models.\u00a0 More information can be... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2024\/nadia-is-the-winner-of-the-peoples-choice-3mt-competition\/\"><p class=\"news__date news__date--archive\">Saturday, June 1, 2024<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Nadia is the winner of the &#8216;People\u2019s Choice&#8217; 3MT competition!<\/h3><p class=\"news__excerpt news__excerpt--archive\">Nadia did an excellent job at the annual Carleton 3MT competition presenting her research with the talk Breath of Life\u00a0in just 3 minutes. She ended up winning the People&#039;s Choice award in the 2024 edition. The lab was also represented by T\u00fcnde who ended up being a finalist, presenting \u00a0Development of a 3D \u2018Lung-on-a-Chip\u2019... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2023\/natasha-has-been-awarded-two-national-scholarships\/\"><p class=\"news__date news__date--archive\">Thursday, September 28, 2023<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Natasha has been awarded two(!!) national scholarships<\/h3><p class=\"news__excerpt news__excerpt--archive\">Natasha Kunchur, a PhD student in our team, has been awarded two highly competitive national scholarships! Natasha accepted the award sponsored by the Canadian Allergy, Asthma and Immunology Foundation (CAAIF), and the Canadian Institutes of Health Research Institute of Circulatory and Respiratory Health (CIHR-ICRH). The award is supporting her... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2023\/dr-mostaco-guidolin-is-now-a-canada-research-chair\/\"><p class=\"news__date news__date--archive\">Thursday, September 28, 2023<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Dr. Mosta\u00e7o-Guidolin is now a Canada Research Chair!<\/h3><p class=\"news__excerpt news__excerpt--archive\">Dr. Mosta\u00e7o-Guidolin was awarded a Tier 2 Canada Research Chair in the area of Imaging and Biomaterials Characterization. With her great team, Dr. Mosta\u00e7o-Guidolin is developing imaging methods to understand fibrosis better and its role in chronic lung diseases. The team is focused on combining 3D bioprinting and optical microscopy, looking at... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2023\/new-paper-alert-3d-bioprinting-vascular-networks-2\/\"><p class=\"news__date news__date--archive\">Thursday, July 13, 2023<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Poster Competition Winners at the TEAM Hub Workshop!<\/h3><p class=\"news__excerpt news__excerpt--archive\">The 1st TEAM Hub Workshop happened at Carleton University on June 26-28th, 2023. We had a chance to listen to amazing talks in several areas, connect with experts from different institutions and of course, visit posters presented by several trainees. The research presented by all trainees was very interesting and the poster judges had... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2023\/winner-of-outstanding-research-competition-at-cmbec45\/\"><p class=\"news__date news__date--archive\">Wednesday, May 24, 2023<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Winner of &#8216;Outstanding Research Competition&#8217; at CMBEC45!<\/h3><p class=\"news__excerpt news__excerpt--archive\">Last week, Dr. Mosta\u00e7o-Guidolin was in Vancouver BC, participating in the 45th Canadian Medical and Biological Engineering Conference. Besides being lucky to have nothing less than perfect sunny weather on the beautiful West Coast, the team was awarded the 1st prize for the &#039;Outstanding Research Competition&#039;, with the work titled: Visualization... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2023\/new-paper-alert-3d-bioprinting-vascular-networks\/\"><p class=\"news__date news__date--archive\">Wednesday, March 1, 2023<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">New paper alert: 3D bioprinting vascular networks<\/h3><p class=\"news__excerpt news__excerpt--archive\">Dr. Mosta\u00e7o-Guidolin and her collaborators from the NRC, uOttawa, and the Department of Physics published a very interesting paper combining a novel collagen-based bio-ink to trigger angiogenesis. They looked into the ECM remodelling using optical microscopy! If you want to read the work, please check it here. Angiogenesis driven extracellular... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2023\/new-paper-alert-atherosclerotic-plaque-classification-using-ml\/\"><p class=\"news__date news__date--archive\">Tuesday, February 28, 2023<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">New paper alert: Atherosclerotic plaque classification using ML<\/h3><p class=\"news__excerpt news__excerpt--archive\">Congratulations to Natasha! She published her first research paper about the application of machine learning to characterize atherosclerotic lesions, imaged with CARS microscopy. For more information, please visit this page. Development of an image classification pipeline for atherosclerotic plaques assessment using supervised machine learning... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2023\/new-paper-alert-2\/\"><p class=\"news__date news__date--archive\">Sunday, February 26, 2023<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">New paper alert: bioengineering lungs<\/h3><p class=\"news__excerpt news__excerpt--archive\">Congratulations to Shahad on publishing her first review paper about methods to bioengineer artificial lung tissues. For more information, please visit this page. Bioengineering lungs: An overview of current methods, requirements, and challenges for constructing scaffolds Chronic respiratory diseases remain a significant health burden worldwide.... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2023\/defense-alert\/\"><p class=\"news__date news__date--archive\">Sunday, February 26, 2023<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Defense Alert!<\/h3><p class=\"news__excerpt news__excerpt--archive\">After a long journey, facing all the challenges associated to the COVID-19 pandemic, lab closures, delays...she successfully completed her project titled: &quot;Morphological Effects of the Microenvironment Structure on Human Fetal Lung Fibroblast Cells&quot;. Congratulations to Shahad on successfully defending her... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2022\/we-have-a-3-minute-thesis-awardee\/\"><p class=\"news__date news__date--archive\">Friday, April 8, 2022<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">We have a 3 Minute Thesis awardee!!!<\/h3><p class=\"news__excerpt news__excerpt--archive\">On April 6th, Carleton University hosted its annual 3 Minute Thesis (3MT) competition and we had a representative from our lab there. Natasha Kunchur presented her talk &#039;Asthma: The Breath Taking Experience&#039; and was awarded 3rd place in the competition! You can find the full results here. Great job, Natasha!... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2022\/congratulations-natasha\/\"><p class=\"news__date news__date--archive\">Friday, April 8, 2022<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Congratulations Natasha!<\/h3><p class=\"news__excerpt news__excerpt--archive\">Natasha has been awarded the Ontario Graduate Scholarship! Natasha&#039;s work is related to developing machine learning-based methods to identify biomarkers related to tissue remodelling happening in asthma. Congratulations,... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2021\/upcoming-talk-ingenious-talks-online\/\"><p class=\"news__date news__date--archive\">Tuesday, October 19, 2021<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">Upcoming talk: Ingenious Talks Online!<\/h3><p class=\"news__excerpt news__excerpt--archive\">Are you interested in learning more about state-of-the-art research technologies? How 3D-bioprinting and optical microscopy can be combined to tell us more about what is happening within biological tissues? What is happening inside of asthmatic airways? How different they are compared to healthy ones? Join us on Nov.3rd at 12:00 pm EST to find... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2021\/we-have-masc-and-phd-positions-open\/\"><p class=\"news__date news__date--archive\">Tuesday, October 5, 2021<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">We have MASc and PhD positions open!<\/h3><p class=\"news__excerpt news__excerpt--archive\">Interested in the areas of tissue engineering or image processing? We have 3 positions open. Please check the details... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2021\/new-paper-alert\/\"><p class=\"news__date news__date--archive\">Monday, August 9, 2021<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">New paper alert: ECM visualization using microscopy<\/h3><p class=\"news__excerpt news__excerpt--archive\">We have just published a new review explaining how different microscopy modalities can be used to image components of the extracellular matrix. Congratulations to Josh on publishing his first peer-reviewed paper! For more information, please visit this page. Optical Microscopy and the Extracellular Matrix Structure: A Review Biological tissues are... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2021\/some-4th-year-projects-are-available-2\/\"><p class=\"news__date news__date--archive\">Thursday, August 5, 2021<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">We have a PhD position open!<\/h3><p class=\"news__excerpt news__excerpt--archive\">If you are interested in joining us, we are currently recruiting a PhD student in the area of tissue engineering \/ 3D bioprinting. Please check the ad and details... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><div class=\"news news--archive u-width-limited\"><a class=\"news__link  news__link--archive\" href=\"https:\/\/carleton.ca\/mostacoguidolin\/2020\/example-news-post\/\"><p class=\"news__date news__date--archive\">Thursday, March 19, 2020<\/p><h3 class=\"news__heading u-hide-in-toc news__heading--archive\" rel=\"bookmark\">New image gallery!<\/h3><p class=\"news__excerpt news__excerpt--archive\">Hello World! Our page is up! If you have a chance, check some of the most beautiful images in our Gallery. There you will find some cool examples of what kind of things we can see using nonlinear optical microscopy. Photons can be magic! Enjoy... <span class=\"news__more-link\">More<\/span><\/p><\/a><\/div><\/div><div class=\"pagination u-clearfix\"><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"<p>Research Overview The main research areas of our group include the characterization of biomaterials, tissues and cells. We want to understand extracellular matrix remodelling and develop in vitro 3D tissue models to understand fundamental mechanisms of diseases. We rely on microscopy and spectroscopy to gather information about the tissue structure at the same time we [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_mi_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research - Leila Mosta\u00e7o-Guidolin, PhD.<\/title>\n<meta name=\"description\" content=\"Research Overview The main research areas of our group include the characterization of biomaterials, tissues and cells. 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