{"id":222,"date":"2020-05-26T18:44:44","date_gmt":"2020-05-26T18:44:44","guid":{"rendered":"https:\/\/carleton.ca\/neuroscience\/?post_type=cu_people&p=222"},"modified":"2025-08-08T14:20:24","modified_gmt":"2025-08-08T18:20:24","slug":"shawn-hayley","status":"publish","type":"cu_people","link":"https:\/\/carleton.ca\/neuroscience\/people\/shawn-hayley\/","title":{"rendered":"Shawn Hayley"},"content":{"rendered":"
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Dr. Shawn Hayley is a full professor in the Department of Neuroscience at Carleton University and a former Canadian Research Chair. He is originally from St. John’s (a.k.a. “The Rock”). He’s an active researcher in many facets of depression and Parkinson’s disease. Outside of the lab, he’s an avid guitarist!<\/p>\n\n\n\n

Eligible to supervise <\/strong>at the undergraduate and graduate level.<\/p>\n\n\n\n

Courses Taught:<\/h3>\n\n\n\n
  • NEUR 3401: Environmental Toxins and the Brain<\/li>
  • NEUR 4305: Brain-Immune Interactions<\/li>
  • NEUR 5100: Graduate Seminar<\/li><\/ul>\n\n\n\n

    Scholarly Work & Research Interests:<\/h3>\n\n\n\n

    The Hayley Lab focuses on how interactions between the brain and immune system may influence the development of psychiatric and neurological conditions, in particular, how stressors impact upon neuro-immune communication to promote emotional and behavioural disturbances. Current projects are also exploring how environmental factors and immune insults may cause brain inflammation that contributes to neurodegeneration.<\/p>\n\n\n\n

    • Neuroimmune mechanisms of depression and Parkinson’s disease<\/li>
    • Environmental toxins and neurodegeneration<\/li>
    • Novel antidepressant strategies involving trophic factors<\/li>
    • Neuro-recovery agents in Parkinson’s disease<\/li>
    • Brain-gut axis and inflammation<\/li><\/ul>\n\n\n\n

      Selected Publications:<\/h3>\n\n\n\n

      Kyle Farmer, Alexa Derksen, Elyn M. Rowe, Ashley M. Thompson, Christopher A. Rudyk, Natalie A. Prowse, Zachary Dwyer, Teresa Fortin, Khaled S. Abd-Elrahman, Stephen S.G. Ferguson, Shawn Hayley (2019). mGluR5 modulation promotes neurorecovery through mTOR in a Parkinson’s model. Mol neurobiology<\/em>, doi: 10.1007\/s12035-019-01818-z.<\/p>\n\n\n\n

      Natalie Prowse, Zach Dwyer, Amanda Thompson, Teresa Fortin, Kristin Elson, H. Robeson, Barbara Fenner, Shawn Hayley (2019). Early life selective knockdown of the TrkB receptor modulates adult stress phenotype. Behavioral Brian Research<\/em>, 27;378:112260.<\/p>\n\n\n\n

      Osborn M, Rustom N, Clarke M, Litteljohn D, Rudyk C, Anisman H, Hayley S* (2013). Antidepressant-like effects of erythropoietin: A focus on hippocampal and behavioral processes. Plos One<\/em>, 8(9):e72813.<\/p>\n\n\n\n

      Mangano EN, Peters S, Litteljohn D, So R, Bethune C, Bobyn J, Clarke M, Hayley S. (2011). Granulocyte macrophage-colony stimulating factor protects against substantia nigra dopaminergic cell loss in an environmental toxin model of Parkinson’s disease. Neurobiol Dis<\/em>. 43(1):99-112.<\/p>\n\n\n\n

      Mount M, Lira A, Alyeason H, Grimes D, Smith P, Slack R, Anisman H, Hayley S, Park DS<\/em> (2007). Central nature of interferon-gamma in microglial mediated loss of dopaminergic neurons. J. Neurosci<\/em>, 27, 3328-3337. *Co-senior authors contributed equally to this manuscript.<\/p>\n","protected":false},"author":2,"featured_media":223,"template":"","meta":{"_acf_changed":false,"cu_people_first_name":"Shawn","cu_people_last_name":"Hayley","cu_people_initials":"","footnotes":"","_links_to":"","_links_to_target":""},"cu_people_type":[30],"cu_people_expertise":[60,40,59],"class_list":["post-222","cu_people","type-cu_people","status-publish","has-post-thumbnail","hentry","cu_people_type-faculty","cu_people_expertise-affective-states","cu_people_expertise-neuroinflammation","cu_people_expertise-neuronal-plasticity"],"acf":{"cu_people_job_title":"Professor","cu_people_degree":"PhD (Carleton)","cu_building":"HS","cu_people_office_num":"5301","cu_people_pronoun":"","cu_people_designation":"","cu_people_email":"shawn_hayley@carleton.ca","cu_people_phone":"613-520-2600","cu_people_phone_ext":"6314","cu_people_linkedin":"","cu_people_bluesky":"","cu_people_twitter":"","cu_people_instagram":"","cu_people_facebook":"","cu_people_website":"https:\/\/hayleylab.weebly.com\/","cu_people_orcid":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/cu_people\/222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/cu_people"}],"about":[{"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/types\/cu_people"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/users\/2"}],"version-history":[{"count":5,"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/cu_people\/222\/revisions"}],"predecessor-version":[{"id":6904,"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/cu_people\/222\/revisions\/6904"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/media\/223"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/media?parent=222"}],"wp:term":[{"taxonomy":"cu_people_type","embeddable":true,"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/cu_people_type?post=222"},{"taxonomy":"cu_people_expertise","embeddable":true,"href":"https:\/\/carleton.ca\/neuroscience\/wp-json\/wp\/v2\/cu_people_expertise?post=222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}