{"id":63957,"date":"2018-07-10T22:00:26","date_gmt":"2018-07-11T02:00:26","guid":{"rendered":"https:\/\/newsroom.carleton.ca\/?post_type=cu_story&#038;p=63957"},"modified":"2025-08-19T09:37:37","modified_gmt":"2025-08-19T13:37:37","slug":"nutritional-supplements-help-run-better","status":"publish","type":"cu_story","link":"https:\/\/carleton.ca\/news\/story\/nutritional-supplements-help-run-better\/","title":{"rendered":"Will a nutritional supplement help you run better?"},"content":{"rendered":"\n<section class=\"w-screen px-6 cu-section cu-section--white ml-offset-center md:px-8 lg:px-14\">\n    <div class=\"space-y-6 cu-max-w-child-max  md:space-y-10 cu-prose-first-last\">\n\n        \n                    \n                    \n            \n    <div class=\"cu-wideimage relative flex items-center justify-center mx-auto px-8 overflow-hidden md:px-16 rounded-xl not-prose  my-6 md:my-12 first:mt-0 bg-opacity-50 bg-cover bg-cu-black-50 pt-24 pb-32 md:pt-28 md:pb-44 lg:pt-36 lg:pb-60 xl:pt-48 xl:pb-72\" style=\"background-image: url(https:\/\/carleton.ca\/news\/wp-content\/uploads\/sites\/162\/conversation-will-a-nutritional-supplement-help-1200w-1b.jpg); background-position: 50% 50%;\">\n\n                    <div class=\"absolute top-0 w-full h-screen\" style=\"background-color:rgba(0,0,0,0.600);\"><\/div>\n        \n        <div class=\"relative z-[2] max-w-4xl w-full flex flex-col items-center gap-2 cu-wideimage-image cu-zero-first-last\">\n            <header class=\"mx-auto mb-6 text-center text-white cu-pageheader cu-component-updated cu-pageheader--center md:mb-12\">\n\n                                    <h1 class=\"cu-prose-first-last font-semibold mb-2 text-3xl md:text-4xl lg:text-5xl lg:leading-[3.5rem] cu-pageheader--center text-center mx-auto after:left-px\">\n                        Will a nutritional supplement help you run better?\n                    <\/h1>\n                \n                            <\/header>\n        <\/div>\n\n                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"absolute bottom-0 w-full z-[1]\" fill=\"none\" viewbox=\"0 0 1280 312\">\n                <path fill=\"#fff\" d=\"M26.412 315.608c-.602-.268-6.655-2.412-13.524-4.769a1943.84 1943.84 0 0 1-14.682-5.144l-2.276-.858v-5.358c0-4.876.086-5.358.773-5.09 1.674.643 21.38 5.84 34.646 9.109 14.682 3.59 28.935 6.858 45.936 10.449l9.874 2.089H57.322c-16.4 0-30.31-.16-30.91-.428ZM460.019 315.233c42.974-10.074 75.602-19.88 132.443-39.867 76.16-26.791 152.063-57.709 222.385-90.663 16.7-7.823 21.336-10.074 44.262-21.273 85.004-41.688 134.719-64.193 195.291-88.413 66.55-26.577 145.2-53.584 194.27-66.765C1258.5 5.626 1281.34 0 1282.24 0c.17 0 .34 27.596.34 61.3v61.299l-2.23.375c-84.7 13.718-165.93 35.955-310.736 84.931-46.494 15.753-65.427 22.076-96.166 32.15-9.102 3-24.814 8.198-34.989 11.574-107.543 35.954-153.008 50.422-196.626 62.639l-6.74 1.876-89.126-.054c-78.135-.054-88.782-.161-85.948-.857ZM729.628 312.875c33.229-10.985 69.248-23.523 127.506-44.207 118.705-42.223 164.596-57.709 217.446-73.302 2.62-.75 8.29-2.465 12.67-3.751 56.19-16.772 126.94-33.597 184.17-43.671 5.07-.91 9.66-1.768 10.22-1.875l.94-.161v170.236l-281.28-.054H719.968l9.66-3.215ZM246.864 313.411c-65.041-2.251-143.047-12.11-208.432-26.256-18.375-3.965-41.73-9.538-42.202-10.074-.171-.214-.257-21.38-.214-47.046l.129-46.618 6.654 3.697c57.313 32.043 118.491 56.531 197.699 79.143 40.313 11.521 83.459 18.058 138.669 21.059 15.584.857 65.685.857 81.14 0 33.744-1.876 61.306-4.93 88.396-9.806 6.396-1.126 11.634-1.983 11.722-1.929.255.375-20.48 7.769-30.999 11.038-28.592 8.948-59.288 15.646-91.873 20.147-26.36 3.59-50.015 5.627-78.35 6.698-15.584.59-55.209.59-72.339-.053Z\"><\/path>\n                <path fill=\"#fff\" d=\"M-3.066 295.067 32.06 304.1v9.033H-3.066v-18.066Z\"><\/path>\n            <\/svg>\n            <\/div>\n\n    \n\n    <\/div>\n<\/section>\n\n<p>Whether you jog to keep fit or compete in marathons, the physically demanding sport of running can deplete the body of essential nutrients.  <\/p>\n\n\n\n<p>During a race like a half-marathon, a runner\u2019s metabolism   \u2014 or ability to convert food and internal resources into energy   \u2014 must work much harder to keep up with increased demand.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/metabolite\" target=\"_blank\" rel=\"noopener noreferrer\">Metabolites are essential molecules that flow through the blood<\/a> to keep the body functioning. Some of these hard-working metabolites are <a href=\"https:\/\/doi.org\/10.1152\/ajpendo.1998.275.1.E73\" target=\"_blank\" rel=\"noopener noreferrer\">amino acids that are absorbed and converted into protein needed for muscle strength and endurance<\/a>.<\/p>\n\n\n\n<p>During times of high demand, if nutrient intake is incomplete, <a href=\"https:\/\/www.nature.com\/subjects\/nutritional-supplements\" target=\"_blank\" rel=\"noopener noreferrer\">nutritional supplements<\/a> can help fill the gaps.  <\/p>\n\n\n\n<p>But how do you know if you need a nutritional supplement? It could all depend on your metabolism. And our team of scientists from the Carleton Mass Spectrometry Centre at Carleton University and Ottawa-based Staterra Inc. <a href=\"http:\/\/oce-ontario.org\/projects%20and%20https:\/\/staterra.ca\/research\/\" target=\"_blank\" rel=\"noopener noreferrer\">have set out to research this<\/a>.<\/p>\n\n\n\n<h2 id=\"no-scientific-consensus\" class=\"wp-block-heading\">No scientific consensus<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>Endurance runners who train intensely lose critical metabolites due to increased energy expenditure and increased protein synthesis during the recovery period. As a result, both elite and non-elite athletes experiment with a variety of nutritional supplements in an attempt to improve their physical performance. <\/p>\n\n\n\n<p>Recently, there has been an explosion in these amino acid supplements. There is <a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-publhealth-040617-013638\" target=\"_blank\" rel=\"noopener noreferrer\">very little scientific evidence<\/a> to back up the claims made about many supplements, and yet a wide variety are now being marketed to runners.  <\/p>\n\n\n\n<p>In some cases, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Whey+Protein+Improves+Marathon-Induced+Injury+and+Exercise+Performance+in+Elite+Track+Runners\" target=\"_blank\" rel=\"noopener noreferrer\">amino acid supplementation can improve training sessions<\/a> and <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=The+Supplementation+of+Branched-Chain+Amino+Acids%2C+Arginine%2C+and+Citrulline+Improves+Endurance+Exercise+Performance+in+Two+Consecutive+Days\" target=\"_blank\" rel=\"noopener noreferrer\">recovery in runners<\/a>. However, we must consider that both training and diet can affect metabolism. Few studies investigate this relationship, which could explain why scientific consensus on the ideal supplementation for endurance runners is still highly debated. <\/p>\n\n\n\n<p>If you misuse or take too much of a nutritional supplement it can <a href=\"https:\/\/journals.humankinetics.com\/doi\/abs\/10.1123\/ijsnem.2017-0429\" target=\"_blank\" rel=\"noopener noreferrer\">also hinder your performance and have long-term, unwanted health effects<\/a>, so it\u2019s important to understand and study the science behind any supplement. <\/p>\n\n\n\n<h2 id=\"tailoring-a-smart-supplement\" class=\"wp-block-heading\">Tailoring a \u2018smart supplement\u2019<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>The research team from Staterra Inc. and Carleton University <a href=\"http:\/\/oce-ontario.org\/projects%20and%20https:\/\/staterra.ca\/research\/\" target=\"_blank\" rel=\"noopener noreferrer\">has set out to quantify exercise-induced changes in several metabolites in the body<\/a>.  <\/p>\n\n\n\n<p>Using the technique of <a href=\"https:\/\/www.asms.org\/about-mass-spectrometry\" target=\"_blank\" rel=\"noopener noreferrer\">mass spectrometry<\/a>, methods have been developed to examine metabolites extracted from dried blood samples of athletes at set intervals over the course of a long-distance run. <\/p>\n\n\n\n<p>This leading-edge technique allows for easy identification of important metabolites required during physical activity. With this information, a \u201csmart supplement\u201d can be tailored to aid in efficient performance and recovery.<\/p>\n\n\n\n<p>Only the necessary and required metabolites are included   \u2014 to avoid burdening the athlete\u2019s body with excretion of unnecessary components. <\/p>\n\n\n\n<h2 id=\"focus-on-metabolic-effect\" class=\"wp-block-heading\">Focus on metabolic effect<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>Significant knowledge gaps exist regarding the ways that metabolites, such as amino acids, impact athletic performance and recovery. <\/p>\n\n\n\n<p>This study attempts to fill in these gaps by determining whether there is a specific metabolic pattern in endurance runners. To paint a clearer picture of what is happening to amino acids during endurance training, participants in the study do not take any type of amino acid supplementation. <\/p>\n\n\n\n<p>Preliminary data indicate a clear pattern in several metabolites. More surprisingly, the data show that several amino acids, which are currently very popular as fitness supplements, are dependent on the individual. This means that different athletes would have a different metabolic pattern as they exercise. This may explain why some athletes thrive on fitness supplements while others do not.<\/p>\n\n\n\n<p>Our study suggests a new and innovative approach to fitness supplementation, where the metabolic changes at the cellular level are identified   \u2014 to develop supplements that will enhance performance, increase recovery and prevent injury. <\/p>\n\n\n\n<p>Focusing on metabolic effects during physical activity should be the new norm in developing safe and efficient supplements.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><\/p>\n\n\n\n<p>This article is republished from <a href=\"https:\/\/theconversation.com\/institutions\/carleton-university-900\" target=\"_blank\" rel=\"noopener noreferrer\">The Conversation<\/a> under a Creative Commons license. Carleton University is a member of this unique digital journalism platform that launched in June 2017 to boost visibility of Canada\u2019s academic faculty and researchers. Interested in writing a piece? Please contact <a href=\"mailto:steven.reid3@carleton.ca\">Steven Reid<\/a> or <a href=\"https:\/\/theconversation.com\/become-an-author\" target=\"_blank\" rel=\"noopener noreferrer\">sign up to become an author<\/a>.<\/p>\n\n\n\n<p><em>All photos provided by The Conversation from various sources.<\/em><\/p>\n\n\n\n<p>&#8212;<br>\n<a href=\"https:\/\/newsroom.carleton.ca\/\">Carleton Newsroom<\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/counter.theconversation.com\/content\/98524\/count.gif?distributor=republish-lightbox-basic\" alt=\"The Conversation\"\/><\/figure>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Whether you jog to keep fit or compete in marathons, the physically demanding sport of running can deplete the body of essential nutrients. During a race like a half-marathon, a runner\u2019s metabolism \u2014 or ability to convert food and internal resources into energy \u2014 must work much harder to keep up with increased demand. Metabolites [&hellip;]<\/p>\n","protected":false},"author":410,"featured_media":64024,"template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"cu_story_type":[1623],"cu_story_tag":[],"class_list":["post-63957","cu_story","type-cu_story","status-publish","has-post-thumbnail","hentry","cu_story_type-expert-perspectives"],"acf":{"cu_post_thumbnail":"blueprint"},"_links":{"self":[{"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/cu_story\/63957","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/cu_story"}],"about":[{"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/types\/cu_story"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/users\/410"}],"version-history":[{"count":3,"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/cu_story\/63957\/revisions"}],"predecessor-version":[{"id":64026,"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/cu_story\/63957\/revisions\/64026"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/media\/64024"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/media?parent=63957"}],"wp:term":[{"taxonomy":"cu_story_type","embeddable":true,"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/cu_story_type?post=63957"},{"taxonomy":"cu_story_tag","embeddable":true,"href":"https:\/\/carleton.ca\/news\/wp-json\/wp\/v2\/cu_story_tag?post=63957"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}