{"id":728,"date":"2026-09-21T14:28:05","date_gmt":"2026-09-21T18:28:05","guid":{"rendered":"https:\/\/carleton.ca\/smithlab\/?post_type=cu_people&#038;p=728"},"modified":"2026-09-21T14:39:12","modified_gmt":"2026-09-21T18:39:12","slug":"jacob-clarke-2","status":"publish","type":"cu_people","link":"https:\/\/carleton.ca\/smithlab\/people\/jacob-clarke-2\/","title":{"rendered":"Jacob Clarke"},"content":{"rendered":"<header class=\"mb-6 cu-pageheader cu-component-updated md:mb-12\">\n    <h1 class=\"cu-prose-first-last font-semibold !mt-2 mb-4 md:mb-6 text-3xl md:text-4xl lg:text-5xl lg:leading-[3.5rem] relative after:absolute after:h-px after:bottom-0 pb-5 after:w-10 after:bg-cu-red after:left-px\">\n                    \n             \n                \n            <\/h1>\n\n    \n    <\/header>\n\n\n\n\n\n<p class=\"wp-block-paragraph\">M.Sc. Candidate<\/p>\n\n\n\n<h2 id=\"about-me\" class=\"wp-block-heading\">About Me<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">My research focuses on utilizing lipids to gain insight into the subtle differences between biological systems. Specifically, I use untargeted lipid relative quantification to compared how specific lipid species change in response to stimuli. To acquire this data, I typically perform a lipid extraction followed by analysis with HPLC-Q-ToF and GC-MS for lipid and sterol analysis respectively.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For example, I investigated the impact of TGF-\u03b2 on the lipid profile of human lung fibroblasts and whether asthma resulted in a distinct response. This project was in collaboration with The Tissue Engineering &amp; Applied Materials (TEAM) Hub. The data acquired provided a comprehensive snapshot of the cell biochemistry and accurately informed further targeted biochemical analyses.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I am always looking for new collaboration opportunities or ideas to improve workflows. If you&#8217;re interested in my work please reach out to my LinkedIn (<a href=\"https:\/\/can01.safelinks.protection.outlook.com\/?url=http%3A%2F%2Fwww.linkedin.com%2Fin%2Fjacobhclarke&amp;data=05%7C02%7CChristianRosales%40cunet.carleton.ca%7C218cc1b0b9944caa3cd608df17ffd52c%7C6ad91895de06485ebc51fce126cc8530%7C0%7C0%7C639256059789720911%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=fo6E1fQijdd1LgnZdHM0cvooH%2BIlrM9OGWDSIvtMAAw%3D&amp;reserved=0\">www.linkedin.com\/in\/jacobhclarke<\/a>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A fun fact about me is that I am a competitive curler and have secured back-to-back U Sports silver medals for the Carleton Raven&#8217;s in 2025 &amp; 2026.<\/p>\n\n\n\n<h2 id=\"publications\" class=\"wp-block-heading\">Publications<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Menard, J.A., Roberts, J.A., <strong class=\"myprefix-text-bold\">Clarke, J.H.<\/strong>, Rudd, K.E.A., Rosales, C.A., Smith, J.C. (2026) LC-MS FADE: Leveraging Untargeted Lipidomics Data for Fatty Acid Profiling. 98(28):20789\u201320800. doi: 10.1021\/acs.analchem.6c01325<\/p>\n","protected":false},"author":620,"featured_media":722,"template":"","meta":{"_acf_changed":false,"cu_people_first_name":"Jacob","cu_people_last_name":"Clarke","cu_people_initials":"JC","footnotes":"","_links_to":"","_links_to_target":""},"cu_people_type":[32],"cu_people_expertise":[],"class_list":["post-728","cu_people","type-cu_people","status-publish","has-post-thumbnail","hentry","cu_people_type-msc"],"acf":{"cu_people_job_title":"","cu_people_degree":"","cu_building":"","cu_people_office_num":"","cu_people_pronoun":"","cu_people_designation":"","cu_people_email":"","cu_people_phone":"","cu_people_phone_ext":"","cu_people_linkedin":"","cu_people_bluesky":"","cu_people_twitter":"","cu_people_instagram":"","cu_people_facebook":"","cu_people_website":"","cu_people_orcid":""},"_links":{"self":[{"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/cu_people\/728","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/cu_people"}],"about":[{"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/types\/cu_people"}],"author":[{"embeddable":true,"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/users\/620"}],"version-history":[{"count":2,"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/cu_people\/728\/revisions"}],"predecessor-version":[{"id":730,"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/cu_people\/728\/revisions\/730"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/media\/722"}],"wp:attachment":[{"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/media?parent=728"}],"wp:term":[{"taxonomy":"cu_people_type","embeddable":true,"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/cu_people_type?post=728"},{"taxonomy":"cu_people_expertise","embeddable":true,"href":"https:\/\/carleton.ca\/smithlab\/wp-json\/wp\/v2\/cu_people_expertise?post=728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}