Publications

PUBLICATIONS

Cassol E, Misra V, Dutta A, Morgello S, Kirk G, Mehta S, and Gabuzda D. Altered monoamine and acylcarnitine metabolism in HIV-positive and HIV-negative subjects with depression. Submitted to JAIDS (under revision).

Malherbe G, Steel HC, Cassol S, de Oliveira T, Seebregts CJ, Anderson R, Cassol E, and Rossouw TM. Circulating biomarkers of immune activation distinguish viral suppression from nonsuppression in HAART-treated patients with advanced HIV-1 subtype C infection. Mediators Inflamm. 2014;2014:198413

Cassol E, Misra V, Dutta A, Morgello S, and Gabuzda D. CSF Metabolomics Reveals Altered Waste Clearance and Accelerated Aging in HIV Patients with Neurocognitive Impairment. AIDS. Jul 17, 2014; 28(11): 1579–1591.

Cassol E, Misra V, Morgello S, and Gabuzda D. Applications and Limitations of Inflammatory Biomarkers for Studies on Neurocognitive Impairment in HIV Infection. J Neuroimmune Pharmacol. 2013 Dec; 8(5):1087-97.

Cassol E, Malfeld S, Mahasha P, Bond R, Slavik T, Seebregts C, Poli G, Cassol S, van der Merwe S, Rossouw T. Impaired CD4+ T cell restoration in the small vs. large intestine of HIV-1+ South Africans receiving combination antiretroviral therapy. J Infect Dis. 2013 Oct 1;208(7):1113-22.

Cassol E, Misra V, Holman A, Kamat A, Morgello S, and Gabuzda D. Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors. BMC Infect Dis. 2013 May 4;13:203.

Cassetta L, Kajaste-Rudnitski A, Coradin T, Saba E, Chiara GD, Barbagallo M, Graziano F, Alfano M, Cassol E, Vicenzi E, Poli G. M1 polarization of human monocyte-derived macrophages restricts pre-and post-integration steps of HIV-1 replication. AIDS. 2013 Apr 26. (Epub ahead of print).

Cassol E, Cassetta L, Rizzi C, Alfano M, Poli G. Dendritic Cell-Specific ICAM-3 Grabbing Nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitro. AIDS 2013; 27(5):707-16.

Kamat A, Misra V, Cassol E, Ancuta P, Yan Z, Li C, Morgello S, Gabuzda D. A plasma biomarker signature of immune activation in HIV patients on antiretroviral therapy. PLoS One 2012; 7(2):e30881.

Cassetta L, Cassol E, Poli G. Macrophage polarization in health and disease. Scientific World Journal 2011; 11:2391-402.

Cassol E, Rossouw T, Seebregts C, Cassol S. Microbial translocation: A marker of advanced HIV-1 infection and a predictor of treatment failure? J Infect Dis 2011;203(5):747-48.

Cassol E, Malfeld S, Mahasha P, van der Merwe S, Cassol S, Seebregts C, Alfano M, Poli G, Rossouw T. Persistent microbial translocation and immune activation in HIV-1-infected South Africans on combination antiretroviral therapy (cART). J Infect Dis 2010;202(5):722-33.

Cassol E, Cassetta L, Alfano M, Poli G. Macrophage polarization and HIV-1 infection. J Leukoc Biol 2010;87:599-608.

Cassol E, Cassetta L, Rizzi C, Alfano M, Poli G. M1 and M2a polarization of human monocyte-derived macrophages inhibits HIV-1 replication by distinct mechanisms. J Immunol 2009: 182:6237-46.

Mosam A, Hurkchand HP, Cassol E, Page T, Cassol S, Aboobaker J, Dawood H, Friedland GH, Coovadia HM. Increased prevalence and severity of HIV-1-associated Kaposi’s sarcoma among young women in South Africa. Int J STD AIDS 2008;19:400-5.

Elia C, Cassol E, Sidenius N, Blasi F, Castagna A, Poli G, Alfano M. Inhibition of HIV replication by plasminogen activator is dependent upon vitronectin-mediated cell adhesion. J Leukoc Biol 2007; 82(5):1212-20.

Mosam A, Sathar MA, Dawood H, Cassol E, Esterhuizen TM, Coovadia HM, Effect of GB virus C co-infection on response to generic HAART in African patients with HIV-1 clade C infection. AIDS 2007;21(10):1377-1379.

Cassol E, Alfano M, Biswas, P, Poli G. Monocyte-derived-macrophages and myeloid cell lines as targets of HIV-1 replication and persistence. J Leukoc Biol 2006;80(5):1018-30.

Cassol E, Page T, Mosam A, Friedland G, Jack C, Lalloo U, Kopetka J, Patterson B, Esterhuizen T, Coovadia HM. Therapeutic response of HIV-1 subtype C in African patients co-infected with either Mycobacterium Tuberculosis, or HHV-8. J Infect Dis 2005; 191(13):324-32.

Cassol E, Mosam A, Friedland G, Coovadia HM and the START and HIV-1/KS Study Groups. Therapeutic response of HIV-1 Subtype C in African patients. J Infect Dis 2005: 192:187.

Mosam A, Goga Y, Thejpal R, Cassol E, Page T, Cassol S, Aboobaker J, Coovadia HM. Lymph-adenopathy, pnuemonia and HIV – a common trio, and uncommon outcome. Lancet 2005;365: (9455)266.

Mosam A, Cassol E, Page T, Bodasing U, Cassol S, Dawood H, Friedland GH, Scadden DT, Aboobaker J, Jordaan JP, Lalloo U, Esterhuizen TM, Coovadia HM. Generic antiretroviral efficacy in AIDS associated Kaposi’s sarcoma in sub-Saharan Africa. AIDS 2005;19(4):441-3.