Apoptosis Research
Useful list of apoptosis inducers and inhibitors and their references.
http://www.twcbiosearch.com/rnd/other/bapop.html
Very useful Apoptosis review page.
http://www.biology-pages.info/A/Apoptosis.html
Cancer Research
Cancer Genome Anatomy Project: database of the genes responsible for cancer, N.I.H.
http://www.ncbi.nlm.nih.gov/ncicgap/
Cell & Stem Cell Biology Research
Informational resources for cellular and molecular biology.
http://www.cellbio.com/
Stem Cell Information. A National Institues of Health maintained site about resources, funding and policy concerning stemcells.
http://stemcells.nih.gov/index.asp
National Stem Cell Resource site, links to protocols, methods and terminology.
http://stemcells.atcc.org/
Human and Animal Cell Lines. A comprehensive database of characterized human and animal cell lines.
http://www.biotech.ist.unige.it/cldb/cname-1c.html
Cell signaling networks database for human cells; pathways are interactively represented by computerized graphics, NIHS, Japan.
http://geo.nihs.go.jp/csndb/
ATCC catalog of cell lines including hybridomas that produce a broad spectrum of antibodies
http://www.atcc.org/
Proteases and protease inhibitors, University of Tours, France.
http://delphi.phys.univ-tours.fr/Prolysis/
Mike Clark’s Immunoglobulin Structure Home Page. This is a great site for extensive diagrams and 3D models of various Ig structures.
http://www.path.cam.ac.uk/~mrc7/igs/mikeimages.html
Cell Migation Informational Consortium, a wonderful collection of reviews, molecules and pathways.
http://www.cellmigration.org/sciResearchMolcPaths.htm
A good informational site for the study of Angiogenesis.
http://www.med.unibs.it/~airc/angiogen.html
Gateway to information, methods and definitions on Adhesion molecules of all kinds.
http://www.neuro.wustl.edu/neuromuscular/lab/adhesion.htm
Excellent search database for cell markers and finding what markers are expressed on what celltype.
http://www.vetmed.wsu.edu/tkp/search.aspx
Cell Biology website references for students and teachers.
http://www.hoflink.com/~house/cellstructure.html
Wonderful table for ADAM proteins with links to the sequences.
http://www.people.virginia.edu/~jw7g/Table_of_the_ADAMs.html
ECM research information for all the ECM proteins (collagens, Fibronectin, laminins etc.).
http://www.indstate.edu/thcme/mwking/extracellularmatrix.html
Wonderful site for anything on human transporter proteins.
http://lab.digibench.net/transporter/
Review of the method of immunoprecipitation and discussion of it.
http://dps.ufl.edu/hansen/protocols/imp98.prt.htm
Excellent review of Integrin Signaling.
http://www.geocities.com/CollegePark/Lab/1580/integrin.html
Cell Surface/CD Marker Resources
Comprehensive list of CD Markers and descriptions of function and tissue distribution (with staining images)
http://pathologyoutlines.com//cdmarkers.html
Excellent search database for cell markers and finding what markers are expressed on what celltype.
http://www.vetmed.wsu.edu/tkp/search.aspx
Excellent resource for FACS methods and protocols.
http://www.orbigen.com/protocols/FACS.html
Disease & Diagnostic Resources
Extensive annotations of ‘hot molecules’ that may play crucial roles in common diseases, Weizmann Institute.
http://bioinformatics.weizmann.ac.il/hotmolecbase/hotmolec.htm
GeneCards: a database of human genes, their products and their involvement in disease, Weizmann Institute
http://bioinfo.weizmann.ac.il/cards/
Positionally cloned human disease genes, N.I.H.
http://www.ncbi.nlm.nih.gov/Disease_Genes/m97hdt0.html
A wonderful information and methods site for research in virology.
http://virology-online.com/index.htm
Alzforum Alzheimer Resarch Forum Home Page. A very active site with many comparisons of antibodies against various Alzheimer related targets.
http://www.alzforum.org/home.asp
Huge resource of information on all kinds of neurobiology related diseases and pathology.
http://www.neuro.wustl.edu/neuromuscular/alfindex.htm
Identification of yeast genes whose mRNA levels are regulated by the cell cycle, Stanford.
http://genome-www.stanford.edu/cellcycle/
Predictions of GalNAc O-glycosylation sites in mammalian proteins, Technical University of Denmark.
http://www.cbs.dtu.dk/services/NetOGlyc/
AMA’s site for CPT codes and information.
http://www.ama-assn.org/ama/pub/category/3884.html
Gateways to Large Online Informational Resources
NCBI Homepage
http://www.ncbi.nlm.nih.gov/Genbank/GenbankSearch.html
Swiss-Prot Protein Knowledgebase. Search various protein databases including the NiceProt anaotated view of Swiss-Prot Database entries.
http://us.expasy.org/sprot/
ExPASy Molecular Biology Server. Links to Databases, Tools and Software packages
http://us.expasy.org/
The AfCS-Nature Signaling Gateway is a comprehensive resource for information about cell signaling, Alliance for Cell Signaling and the Nature Publishing Group.
http://www.signaling-gateway.org/
Biomolecular Interaction Network Database serves full descriptions of interactions of proteins, nucleic acids and small molecules.
http://www.blueprint.org/bind/bind.php
Cytokines online encyclopedia, University of Munich.
http://www.copewithcytokines.de/
MEROPS the peptidase database information resource.
http://merops.sanger.ac.uk/
MRI atlas of mouse development online.
http://mouseatlas.caltech.edu/
LocusLink provides a single query interface to curated sequence and descriptive information about genetic loci. It presents information on official nomenclature, aliases, sequence accessions, phenotypes, EC numbers, MIM numbers, UniGene clusters, homology, map locations, and related web sites.
http://www.ncbi.nlm.nih.gov/LocusLink/index.html
Molecular Biology Shortcuts, links to molecular and cellular biology methods and databases.
http://www.mbshortcuts.com/index.shtml
Computational Biology and Informatics Laboratory at the University of Pennsylvania
http://www.cbil.upenn.edu
Gateway to information, methods and definitions on Adhesion molecules of all kinds.
http://www.neuro.wustl.edu/neuromuscular/lab/adhesion.htm
Huge assortment of informational biology related links.
http://www.biozone.co.uk/links.html
Cell Migation Informational Consortium, a wonderful collection of reviews, molecules and pathways.
http://www.cellmigration.org/sciResearchMolcPaths.htm
Wonderful site for anything on human transporter proteins.
http://lab.digibench.net/transporter/
Gateway to the WWW. Virtual Library
http://vlib.org/
General Science Resources
On-Line Dictionary of Cell and Molecular Biology
http://www.mblab.gla.ac.uk/dictionary/
Useful page detailing the accept names for various mammalian animals and animal sexes.
http://www2.biology.ualberta.ca/uamz.hp/MamName.html
Biology website references for students and teachers.
http://www.hoflink.com/~house/cellstructure.html
A wonderful information and methods site for research in virology
http://virology-online.com/index.htm
Online atlas of mouse embryos.
http://genex.hgu.mrc.ac.uk/Atlas/intro.html
Excellent review for fixation and fixation related issues.
http://home.primus.com.au/royellis/fix.htm
Kimball’s biology online, excellent resource for all sorts of biological information.
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/W/Welcome.html
Wonderful search engine for scientific information of all types.
http://www.scirus.com/srsapp/
Genome & Mutation Databases
GenBank, an annotated database of all publicly available DNA sequences, N.I.H.N.L.M.
http://www.ncbi.nlm.nih.gov/Genbank/GenbankOverview.html
Sequence database of long (>4 kb) human cDNAs, Kazusa DNA Research Institute.
http://www.kazusa.or.jp/huge/index.html
Links to resources for expressed sequence tags analysis, University of Brescia.
http://www.tigem.it/ESTmachine.html
Human Genome Project database, Toronto.
http://www.gdb.org/gdb/
The human genomic research program, Sanger Center.
http://www.sanger.ac.uk/HGP/
TIGR human gene index.
http://www.tigr.org/tdb/tgi/hgi/
Human mitochondrial genome, Emory University.
http://www.mitomap.org/l
The mouse genome, Jackson Laboratory.
http://www.informatics.jax.org/
Drosophila genome project, Berkeley.
http://www.fruitfly.org/
C. elegans genome, Sanger Center.
http://www.sanger.ac.uk/Projects/C_elegans/
S. cerevisiae genome, Stanford.
http://genome-www.stanford.edu/Saccharomyces/
Completely sequenced bacterial genomes and the yeast genome, Universite Claude Bernard, Lyon.
http://pbil.univ-lyon1.fr/emglib/emglib.html
Database of disease-causing mutations in tyrosine kinase domains, links to other mutation databases, University of Tampere.
http://www.uta.fi/imt/bioinfo/KinMutBase/
Atlas of Genetics and Cytogenetics in Oncology and Haematology, dedicated to biological and molecular aspects of cancer and cancer-prone diseases.
http://www.infobiogen.fr/services/chromcancer/index.html
Online Mendelian Inheritance in Man: catalog of human genes and genetic disorders, N.I.H.
http://www4.ncbi.nlm.nih.gov/omim/
Human Gene Mutation Database, Institute of Medical Genetics, Cardiff.
http://archive.uwcm.ac.uk/uwcm/mg/hgmd0.html
Online Mendelian Inheritance in Animals: catalog of animal genes and genetic disorders, University of Sydney
http://www.angis.su.oz.au/Databases/BIRX/omia/
Cancer Genome Anatomy Project: database of the genes responsible for cancer, N.I.H.
http://www.ncbi.nlm.nih.gov/ncicgap/
Links to a number of locus specific mutation databases, N.I.H.
http://www4.ncbi.nlm.nih.gov/Omim/Index/mutation.html
Positionally cloned human disease genes, N.I.H.
http://www.ncbi.nlm.nih.gov/Disease_Genes/m97hdt0.html
Immunohistochemistry Resources
This page contains our online collection of protocols in the fields of general histology, immunhistochemistry, immunofluorescence, in situ hybridization, antigen retrieval, and electron microscopy.
http://www.ihcworld.com/protocol_database.htm
General guidelines for Immunostaining.
http://www.biodesign.com/tables/bio12p.html
Excellent review for fixation and fixation related issues.
http://home.primus.com.au/royellis/fix.htm
Excellent immunohistochemistry methods resource page with links to many, many protocols.
http://icg.cpmc.columbia.edu/cattoretti/Protocol/Immunohistochemistry/mainPageIHC-IF.html
Knockout and Transgenic Mice
List of those genes which have been ablated in mice and the phenotypic effects of these knockouts.
http://www.bioscience.org/knockout/knochome.htm
Transgenic and targeted mutant animal database, Oak Ridge National Laboratory.
http://www.ornl.gov/TechResources/Trans/hmepg.html
Source of mouse strains with transgenes, or with targeted or chemically-induced mutations, The Jackson Laboratory.
http://jaxmice.jax.org/jaxmice-cgi/jaxmicedb.cgi
Neuroscience Research
Neural network predictions of phosphorylation sites in eukaryotic proteins, Technical University of Denmark.
http://www.cbs.dtu.dk/services/NetPhos/
Collaborative effort to build integrated, multidisciplinary models of neurons and neural systems, Yale University.
http://senselab.med.yale.edu/senselab/
Alzforum Alzheimer Resarch Forum Home Page. A very active site with many comparisons of antibodies against various Alzheimer related targets.
http://www.alzforum.org/home.asp
Huge resource of information on all kinds of neurobiology related diseases and pathology.
http://www.neuro.wustl.edu/neuromuscular/alfindex.htm
Online and Literature Search Engines
Google Search Engine, particularly good for science and literature searching.
http://www.google.com/
A very useful site for finding bioreach reagents comparing the various vendor offerings.
http://www.biocompare.com/
SciQuest. A useful search engine for finding a variety of science materials
http://www.sciquest.com/
Excellent reference search engine with links to journals and Medline.
http://journals.bmn.com/medline
NLM’s search service to citations in MEDLINE, with links to online journals and other related databases, N.I.H.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
Free “alerting” service that scans daily updates to the NCBI, Medline and GenBank databases.
http://www.pubcrawler.ie/
Effort to make the world’s scientific and medical literature freely accessible to scientists and to the public around the world.
http://www.publiclibraryofscience.org/
Molecular, Proteomic/Genomic Tools
Proteins. A useful basic reference on protein structure and bonding.
http://www.friedli.com/herbs/phytochem/proteins.html
Protein Calculator. A useful interface for calculating approximate molecular weight of any protein. Developed by Chris Putnam.
http://www.scripps.edu/~cdputnam/protcalc.html
Pedor’s BioMolecular Research Tools. A collection of WWW links to information and services useful to molecular biologists.
http://www.public.iastate.edu/~pedro/research_tools.html
PROW: Protein Reviews on the Web
http://www.ncbi.nlm.nih.gov/prow/
EMBL-EBI HomePage-Links to Protein Sequence Analysis Databases
http://www.ebi.ac.uk/interpro/databases.html
ExPASy Molecular Biology Server. Links to Databases, Tools and Software packages
http://us.expasy.org/
PDB, repository for the processing and distribution of 3-D biological macromolecular structure data.
http://www.rcsb.org/pdb/
PIR-International Protein Sequence Database, a non-redundant, annotated database of protein sequences.
http://www.mips.biochem.mpg.de/proj/protseqdb/
Biology Workbench, an integrated search, modeling and analysis platform that accesses all major protein and nucleic acid databases, University of Illinois
http://workbench.sdsc.edu
Excellent compendium of tools and resources for molecular biology and proteomics, University of California San Diego.
http://www.sdsc.edu/ResTools/cmshp.html
GenBank, an annotated database of all publicly available DNA sequences, N.I.H.N.L.M.
http://www.ncbi.nlm.nih.gov/Genbank/GenbankOverview.html
BLAST (Basic Local Alignment Search Tool), a set of search programs for identifying sequence similarities between protein and nucleotide sequences, N.I.H.N.L.M.
http://www.ncbi.nlm.nih.gov/BLAST/blast_overview.html
PredictProtein is a service for sequence analysis and structure prediction, Heidelberg.
http://www.embl-heidelberg.de/predictprotein/predictprotein.html
Tool for analyzing the domain structure of protein sequences, PFAM consortium: Sanger Centre, Washington University, Karolinska Institute.
http://pfam.wustl.edu/hmmsearch.shtml
Genome Sequencing Center, Washington University
http://genome.wustl.edu/
Online links to molecular sequence analysis tools for nucleotides and proteins, Whitehead Institute.
http://web.wi.mit.edu/bio/pub/biopage2.html
Computerized effort to model molecular interactions, Kyoto University.
http://www.genome.ad.jp/kegg/
Sequence database of long (>4 kb) human cDNAs, Kazusa DNA Research Institute.
http://www.kazusa.or.jp/huge/index.html
Genomic sequences and tools, Max-Planck-Institut f. Biochemie Munich.
http://www.mips.biochem.mpg.de/
Molecular Biology Shortcuts, links to molecular and cellular biology methods and databases.
http://www.mbshortcuts.com/index.shtml
Links to resources for expressed sequence tags analysis, University of Brescia.
http://www.tigem.it/ESTmachine.html
Wonderful set of helpful molecular biology tools and formula calculators.
http://www.changbioscience.com/protocols/recipe.htm
Signal Transduction/Cytokine Research
The AfCS-Nature Signaling Gateway is a comprehensive resource for information about cell signaling, Alliance for Cell Signaling and the Nature Publishing Group.
http://www.signaling-gateway.org/
Scansite predicts phosphorylation sites and specific domain-binding regions within proteins, MIT.
http://scansite.mit.edu
Neural network predictions of phosphorylation sites in eukaryotic proteins, Technical University of Denmark.
http://www.cbs.dtu.dk/services/NetPhos/
Analyses of protein kinases from human, yeast, worm and fly.
http://www.kinase.com/
Signal transduction knowledge environment: resources and information on signal transduction, Science Magazine and Stanford University. Requires Subscription.
http://www.stke.org
Protein Kinase Resource: the genetics, enzymology, and molecular properties of protein kinases, University of California San Diego.
http://pkr.sdsc.edu/html/index.shtml
TRANSPATH information system dedicated to gene-regulatory pathways.
http://transpath.gbf.de/
Biomolecular Interaction Network Database serves full descriptions of interactions of proteins, nucleic acids and small molecules.
http://www.blueprint.org/bind/bind.php
Open resource providing online maps depicting selected signaling pathways.
http://www.biocarta.com/genes/index.asp
Cytokines online encyclopedia, University of Munich.
http://www.copewithcytokines.de/
Links to cytokine, chemokine and related resources, Kumamoto University.
http://cytokine.medic.kumamoto-u.ac.jp/CFC/CFC-links.html
Nuclear Receptor Resource: a collection of databases on the nuclear receptor superfamily, Georgetown University.
http://nrr.georgetown.edu/nrr/NRR1.html
Information system for G protein-coupled receptors.
http://www.gpcr.org/7tm/
Wnt gene homepage, Stanford.
http://www2.stanford.edu/~rnusse/wntwindow.html
Predictions of GalNAc O-glycosylation sites in mammalian proteins, Technical University of Denmark.
http://www.cbs.dtu.dk/services/NetOGlyc/
Cell signaling networks database for human cells; pathways are interactively represented by computerized graphics, NIHS, Japan.
http://geo.nihs.go.jp/csndb/
Excellent review of Integrin Signaling.
http://www.geocities.com/CollegePark/Lab/1580/integrin.html