About the BioImaging and Tissue Engineering Lab

The BioImaging and Tissue Engineering Lab is an interdisciplinary research group that focuses on the development of novel tools to monitor and characterize biochemical and morphological aspects of tissue in non-invasive ways.

Our work relies heavily on optical microscopy and spectroscopy imaging and quantitative data analysis approaches that often involve an understanding of the detailed interactions between light and biological matter. Our approaches exploit linear and non-linear optical phenomena and include light scattering spectroscopy, linear and non-linear microscopy (second harmonic generation, two-photon excited fluorescence, Coherent Anti-Stokes Raman scattering) and Raman spectroscopy.

Specific applications of our work include monitoring extracellular matrix remodelling (especially collagen) and the development of 3D-bioprinted fibrotic tissue models. These projects are pursued with collaborators at Carleton University, the National Research Council Canada, the University of Ottawa, the University of British Columbia – Heart Lung Innovation Centre, and the University of Manitoba.


3D printed human fibrotic model for studying how abnormal mechano-environment may affect fibroblast collagen remodelling

Research Overview

Dr. Mostaço-Guidolin was invited to present an overview of some projects happening at the BioImaging and Tissue Engineering Lab. Watch the recording here.