The main research areas of our group include the characterization of biomaterials, tissues and cells. We want to understand extracellular matrix remodelling and develop in vitro 3D tissue models to understand fundamental mechanisms of diseases. We rely on microscopy and spectroscopy to gather information about the tissue structure at the same time we develop image analysis strategies. The tools we develop are useful in answering relevant biological questions related to the assessment of tissue function during normal and pathological conditions as well as in response to treatments.
- Optical microscopy & spectroscopy
- Extracellular matrix remodelling & fibrosis
- 3D-bioprinting and biomaterials
- Digital image analysis (focus on microscopy and histopathology)
Thursday, July 13, 2023
Poster Competition Winners at the TEAM Hub Workshop!
The 1st TEAM Hub Workshop happened at Carleton University on June 26-28th, 2023. We had a chance to listen to amazing talks in several areas, connect with experts from different institutions and of course, visit posters presented by several trainees. The research presented by all trainees was very interesting and the poster judges had...
Wednesday, May 24, 2023
Winner of ‘Outstanding Research Competition’ at CMBEC45!
Last week, Dr. Mostaço-Guidolin was in Vancouver BC, participating in the 45th Canadian Medical and Biological Engineering Conference. Besides being lucky to have nothing less than perfect sunny weather on the beautiful West Coast, the team was awarded the 1st prize for the 'Outstanding Research Competition', with the work titled: Visualization...
Wednesday, March 1, 2023
New paper alert: 3D bioprinting vascular networks
Dr. Mostaço-Guidolin and her collaborators from the NRC, uOttawa, and the Department of Physics published a very interesting paper combining a novel collagen-based bio-ink to trigger angiogenesis. They looked into the ECM remodelling using optical microscopy! If you want to read the work, please check it here. Angiogenesis driven extracellular...
Tuesday, February 28, 2023
New paper alert: Atherosclerotic plaque classification using ML
Congratulations to Natasha! She published her first research paper about the application of machine learning to characterize atherosclerotic lesions, imaged with CARS microscopy. For more information, please visit this page. Development of an image classification pipeline for atherosclerotic plaques assessment using supervised machine learning...
Sunday, February 26, 2023
New paper alert: bioengineering lungs
Congratulations to Shahad on publishing her first review paper about methods to bioengineer artificial lung tissues. For more information, please visit this page. Bioengineering lungs: An overview of current methods, requirements, and challenges for constructing scaffolds Chronic respiratory diseases remain a significant health burden worldwide....
Sunday, February 26, 2023
After a long journey, facing all the challenges associated to the COVID-19 pandemic, lab closures, delays...she successfully completed her project titled: "Morphological Effects of the Microenvironment Structure on Human Fetal Lung Fibroblast Cells". Congratulations to Shahad on successfully defending her...
Friday, April 8, 2022
We have a 3 Minute Thesis awardee!!!
On April 6th, Carleton University hosted its annual 3 Minute Thesis (3MT) competition and we had a representative from our lab there. Natasha Kunchur presented her talk 'Asthma: The Breath Taking Experience' and was awarded 3rd place in the competition! You can find the full results here. Great job, Natasha!...
Friday, April 8, 2022
Natasha has been awarded the Ontario Graduate Scholarship! Natasha's work is related to developing machine learning-based methods to identify biomarkers related to tissue remodelling happening in asthma. Congratulations,...
Tuesday, October 19, 2021
Upcoming talk: Ingenious Talks Online!
Are you interested in learning more about state-of-the-art research technologies? How 3D-bioprinting and optical microscopy can be combined to tell us more about what is happening within biological tissues? What is happening inside of asthmatic airways? How different they are compared to healthy ones? Join us on Nov.3rd at 12:00 pm EST to find...
Tuesday, October 5, 2021
We have MASc and PhD positions open!
Interested in the areas of tissue engineering or image processing? We have 3 positions open. Please check the details...
Monday, August 9, 2021
New paper alert: ECM visualization using microscopy
We have just published a new review explaining how different microscopy modalities can be used to image components of the extracellular matrix. Congratulations to Josh on publishing his first peer-reviewed paper! For more information, please visit this page. Optical Microscopy and the Extracellular Matrix Structure: A Review Biological tissues are...
Thursday, August 5, 2021
We have a PhD position open!
If you are interested in joining us, we are currently recruiting a PhD student in the area of tissue engineering / 3D bioprinting. Please check the ad and details...