Opportunity

The Therapeutic Pipeline Program is open to industry and academic investigators proposing novel approaches or repositioning approved or clinically safe therapies from other disease indications. Part of our Edmond J. Safra Core Programs for PD Research, the Therapeutic Pipeline Program advances Parkinson’s disease therapeutic and intervention development along the pre-clinical and clinical path.

Therapies aiming to address one of the following treatment challenges:

  • Protection or restoration of degenerating and/or dysfunctional neurons affected in Parkinson’s
  • Alleviation of disabling motor or non-motor symptoms of Parkinson’s not well managed by current treatments
  • Reduction of complications and side effects of current Parkinson’s treatments.

Pharmacological interventions as well as biologic, gene therapy, surgical and non-invasive/non-pharmaceutical approaches are appropriate. MJFF is particularly interested in early stage drug discovery efforts for novel PD relevant targets for which there are limited drug campaigns currently active and efforts focused on developing therapeutics that alleviate non-motor symptoms.

Eligibility

Applications may be submitted by researchers or clinicians in:
U.S. and non-U.S. biotechnology/pharmaceutical companies, or other publicly or privately held for-profit entities; and
U.S. and non-U.S. public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments and eligible agencies of the federal government.
Post-doctoral fellows are not eligible to apply as principal investigators.

Funding Available

Up to $500,000 for Pre-clinical Program
Up to $2,000,000 for Clinical Program
Final budgets will be determined based on review of proposed work and MJFF role.
MJFF may not be able to support all costs for a proposed therapeutic development plan and applicants are encouraged to leverage additional sources of funding and resources. These budgets include direct and indirect costs. For academic and for-profit institutions, no more than 15% or 10%, respectively, may go to indirect costs.

Internal Contacts

For proposal development/substantive review, please contact Heloise Emdon.

Deadlines

Faculty Deadline Consult Heloise Emdon.
OVPRI Approval Form Deadline April 16, 2020
Submission to Sponsor April 23, 2020 by 5pm EST (Pre-Proposal)

Submitting Your Application

  • Step 1) Submit an internal Carleton Approval Form
    Submit an internal Approval Form through our central awards management database CUResearch:
    https://ovpri.research.carleton.ca/Romeo.Researcher/Administrator/Default.aspx
    For a user’s guide on submitting an Approval Form, click here.
  • Step 2) Submit an external application to the granting agency
    Submit an external application to the corresponding grant or award agency. For further details about funding categories, eligibility criteria and deadlines for this opportunity, click here.