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2020-21 Health Sciences Seminar Series – Holcik Lab

March 10, 2020 at 12:00 PM to 1:00 PM

Location:2308 (2nd floor boardroom) Health Sciences Building

Lost in translation – linking protein synthesis to human disease

Presenters:
Dr. Martin Holcik
Krishna Bhattai (PhD candidate)
Angelo Slade (MSc candidate)

Translation, or protein synthesis, is an essential mechanism required to decode cellular information stored in nucleic acids into proteins, the building blocks of cells. It is now well established that cellular stress, both physiologic and pathophysiologic, selectively modulates protein synthesis in order to match the correct protein output to the conditions. The mechanisms allowing this selective control, and their links to human disorders will be presented and discussed.