David Sabatino

Associate Professor

• Ph.D (McGill University)
• 207F Steacie Building, Carleton University
• 1125 Colonel By Drive, Ottawa, ON, K1S 5B6
• Email David Sabatino
• 613-520-2600 ext 4229

• Visit the Website

Current Research

My research interests spans the areas of nucleic acid, peptide and protein chemical biology for developing synthetic biologicals for applications in drug discovery related to anti-cancer activity.

Selected Publications

1.George Hilan, Grace Daniel, Filiz Collak, William Willmore, Bruce McKay and David Sabatino. Cancer-Targeting Peptides Functionalized with Polyarginine Enables GRP78-Dependent Cell Uptake and siRNA Delivery within the DU145 Prostate Cancer Cells. J. Pept. Sci. 2025, 31(3), e70007.

2. Grace Daniel, George Hilan, Lisa Ploeg and David Sabatino. Self-Assembly of Helical-Coiled Amphiphilic Peptide Nanofibers and Inhibition of Fibril Formation by Curcumin. Bioorg. Med. Chem. Lett., 2024; 102, 129682.

3. Nour Nissan, Mitchell Allen, David Sabatino and Kyle Biggar Future Perspective: Harnessing the Power of Artificial Intelligence in the Generation of New Peptide Drugs. Biomolecules. 2024, 14(10), 1303.

4. Dante Descalzi-Montoya, Rachel A. Montel, Keith Smith, Eugenia Dziopa, Andrieh Darwich, Zheng Yang, Constantine Bitsaktsis, Robert Korngold, and David Sabatino.Synthetic Antibody Mimics Based on Cancer-Targeting Immunostimulatory Peptides. ChemBioChem. 2021, 22(9), 1589-1596.

5. David Sabatino. Medicinal Chemistry and Methodological Advances in Peptide-Based Vaccines. J. Med. Chem. 2020, 63(23),14184-14196.