The American Chemical Society invites proposals for a research grant on greener peptide, oligonucleotide and antibody-drug conjugate synthesis (ADC synthesis). They strive to integrate the principles of green chemistry and engineering into the business of drug recovery and production. This grant is meant to support a project that provides novel approaches to improve greenness of peptide, oligonucleotide and ADC synthesis and manufacture.
Opportunity
The goal of this work is to develop strategies for greener synthesis of peptides, oligonucleotides and antibody-drug conjugates. These may include, but are not limited to:
- Reduced chromatography or chromatography-free systems
- Solution phase fragment condensation, preferably optimized to use green solvents
- Alternative synthesis techniques such as Native Chemical Ligation or Chemo Enzymatic Peptide Synthesis
- Hybrid strategies that leverage fermentation for peptide synthesis
- Use of flow chemistry techniques for peptide, oligonucleotide or ADC preparation
- Implementation of membrane-based approaches for purification
Eligibility
- Proposals are accepted from public and private institutions of higher education.
- they must be submitted by email to gcpir@acs.org through the appropriate institutional office
Available Funding
- one grant worth $50,000 USD available for a period of 12 months with a possibility of renewal for a second year
Useful Links
- ACS official Call for Proposal
- ACS funding and awards
Deadlines
| CORIS Internal Deadline for Review | Please contact Heloise Emdon | |
| cuResearch Deadline to CORIS | July 28, 2017 | |
| Submission to Sponsor | August 04, 2017 | 5:00 PM (ET) |
Submitting Your Application
- Applications must be submitted via cuResearch, through which Departmental and Associate Dean’s approval must be provided to complete the online application process.
- More information on cuResearch can be found here.
Internal Contacts
If you would like assistance with proposal development and/or a substantive review of your proposal, please contact Heloise Emdon.