1. Detector For Faster Than Nyquist Transmitted Data Symbols
  2. Enabling Wireless Network Big Data-Driven Personalization Using Zone of Tolerance Modeling and Predictive Analytics
  3. Aptamers as a Therapeutic Tool to Prevent Protein Aggregation In Neurodegenerative Disease
  4. Root Exudate-Activated System for Agrochemical Delivery
  5. A Method for Prevention of Ingress of Hydrogen Isotopes and Their Removal from Components Made from Hydride Forming Metals and Alloys
  6. Independent Control of a Reflected Electromagnetic Wave’s Magnitude and Phase
  7. Salivary Point-Of-Contact Bio-Analyzer

Innovations available for development and licensing opportunities are listed below. We welcome discussion with any potential partner. For more information about these or other opportunities, contact:

Shoma Sinha, PhD
Assistant Director, Innovation and Partnerships
Shoma.Sinha@carleton.ca
Theresa C. White, PhD
Manager—Innovation Transfer, Contracts and Agreements
theresa.white3@carleton.ca
Bhagya Herath
Commercialization Officer
Bhagya.Herath@carleton.ca

Detector For Faster Than Nyquist Transmitted Data Symbols
Overview A Faster-than-Nyquist (FTN) signaling detector for ultra-high-order quadrature-amplitude modulation capable of removing inter-symbol interference and reconstruction of the transmitted data symbols, within the same bandwidth and using the same transmission power of conventional Nyquist signaling.

Inventor(s): Ahmed Ibrahim, Ebrahim Bedeer, and Halim Yanikomeroglu
Benefits
  • Ultra-high QAM data transmission without increased bandwidth or transmit power.
  • Significantly reduced inter-symbol interference (ISI) and bit errors.
Status
 US application:  18/277,449 (int’l filing date 16-Feb-2022)
CA application: 3,208,642 (int’l filing date 16-Feb-2022)Available for licensing and/or development partnerships
Development stage Concept validation complete

Technology Brief

Enabling Wireless Network Big Data-Driven Personalization Using Zone of Tolerance Modeling and Predictive Analytics
Overview A novel method and system for managing and allocating wireless network resources to optimize User satisfaction. The system comprises a wireless base station that employs a ‘zone of tolerance’ machine-learning algorithm to model user satisfaction and optimize allocation of network resources.

Inventor(s): Rawan Alkurd, Halim Yanikomeroglu, and Ibrahim Abualhaol
Benefits
  • A maximum user satisfaction can be achieved with a minimal resources.
  • Resources utilized for more critical applications such as public safety and autonomous cars.
  • Customers will save more money as they do not have to pay for the provided extra bandwidth they do need or use.
Status US patent 11,736,973 issued 22-Aug-2023
CA application 3,111,030 (int’l filing date 29-Aug-2019)
CA application 3,126,091 (filed 27-Jul-21)
EP application 08940587  (int’l filing date 29-Aug-2019)
Available for licensing and/or development partnerships
Development stage
 Concept validation complete

Technology Brief

Aptamers as a Therapeutic Tool to Prevent Protein Aggregation In Neurodegenerative Disease
Overview Novel DNA aptamer sequences that bind to alpha-synuclein monomers and inhibit the formation of larger oligomers associated with neurodegenerative disease such as Parkinson’s Diseases. We have packaged the aptamers in a vehicle capable of crossing the blood brain barrier and binding to alpha synuclein in a mouse model of Parkinson’s disease. Immunofluorescence confirmed delivery of the fluorescently labelled aptamer and its co-localization with an antibody specific for phosphorylated alpha synuclein monomer.

Inventor(s): Maria Cynthia DeRosa, Matthew Richard Holahan, Erin Marie McConnell, Katelyn Victoria Ventura, Joshua Partner Callahan, and Vernon Harold Daniel Hunt
Benefits
  • Compared with conventional antibodies, Aptamers are not typically recognized by the immune system and are neither immunogenic nor toxic molecule.
  • Aptamers can discriminate between different conformations of the same target protein.
  • Can be easily generated by chemical synthesis.
Status
 PCT application number: PCT/CA2018/051335 filed Oct. 22, 2018
US patent 11,814,625 (issued 14-Nov-2023)
CA application number: 3,079,909 (int’l filing date 22-Oct-18)
Available for licensing and/or development partnerships
Development stage
 Concept validation complete

Technology Brief

Root Exudate-Activated System for Agrochemical Delivery
Overview Coated particles for delivering agrochemical to the roots of a plant comprising a cellulose derivative, a fatty acid, and an aptamer that binds specifically to an exudate released by the roots of the plant when the plant is actively taking up nutrients from the soil.  The permeability of the coating increases when the DNA aptamer within coated particles binds to the exudate synchronizing nutrient release with uptake of the nutrients during active growth.

Inventor(s):Juan Schneider, Carlos Monreal, Maria DeRosa, Philip Choi, Emily Mastronardi, Phepafatso Tsae, and Francisco Matus
Benefits
  • Improved nitrogen use efficiency by the plant.
  • Improved crop productivity and/or reduced leaching of fertilizer from soil.
Status US application 17/276,302 (int’l filing date 16-Sept-2019)
CA application 3,112,597 (int’l filing date 16-Sept-2019)
AU application  2019337776 (int’l filing date 16-Sept-2019)
Available for licensing and/or development partnerships
Development stage
  • Concept validation complete

Technology Brief

A Method for Prevention of Ingress of Hydrogen Isotopes and Their Removal from Components Made from Hydride Forming Metals and Alloys
Overview Hydrogen in metals is sometimes a problem because of embrittlement, and methods are sought to reduce the concentration and ingress of hydrogen. Specifically, a method is disclosed to reduce the rate of ingress of hydrogen isotopes and their subsequent concentrations in zirconium alloy pressure tubes in a CANDU reactor where they are joined to the stainless-steel end-fitting, by the addition of a hydrogen getter to the outboard portion of the end fitting. The hydrogen getter can be any material that has a lower chemical potential for hydrogen than zirconium and can be attached to the end fitting so that a free path for hydrogen movement between the zirconium, steel, and getter is produced. Suitable candidate getter materials include zirconium, titanium, niobium, hafnium, vanadium, or yttrium, as metal, metal alloys or metal composites.

Inventor(s): Glenn McRae, Christopher Coleman, and Scott Langille
Benefits
Status CA application 3,007,703 (filed June 18, 2019)
Available for licensing and/or development partnerships
Development stage Concept validation complete

Independent Control of a Reflected Electromagnetic Wave’s Magnitude and Phase
Overview Metasurface reflector comprising an array of unit cells, each of which having independently controllable resistance and capacitance that allows for control of the magnitude and phase of the reflected wave by each unit cell.  In one implementation, the unit cell uses coupled resonators, with each resonator having independently controllable parameters.  By independently adjusting the resistance and the capacitance of the resonators, the magnitude and phase of the reflected wave from each unit cell can be controlled.

Inventor(s): Shulabh Gupta and Ahmed Ashoor
Benefits
  • Provides superior coverage and ultra high-speed communication performance.
  • Can operate on the new 5G frequency spectrum.
  • Can make an object or a target undetectable within a given background achieving electromagnetic (EM) camouflage.
Status US application 18/246,637 (int’l filing date 24-Sept-21)
CA application 3,196,718 (int’l filing date 24-Sept-21)
Available for licensing and/or development parternships
Development stage

Concept validation complete; prototype testing in progress

Technology Brief

Salivary Point-Of-Contact Bio-Analyzer
Overview A reliable, low-cost, non-invasive Point-of-Contact (PoC) device that can utilize non-blood biological samples and quantitatively measure multiple useful biomarkers (hormone, proteins, small molecules) that are associated with health and disease onset/progression. Disposable, cost-effective device with multiplexing capabilities to detect and quantify multiple analytes side-by-side.  Excellent sensitivity and specificity to target analyte, while being independent of presence of additional materials in bio-electrolyte solution. Room temperature storage and device fabrication.

Inventor(s):  Robyn Massey and Ravi Prakash
Benefits
  • Disposable, cost-effective device.
  • Multiplexing capabilities to detect and quantify multiple analytes side-by-side.
  • Low sample volumes required: 10µL for each analysis test.
  • Excellent sensitivity and specificity to target analyte, while being independent of presence of additional materials in bio-electrolyte solution.
  • Broad range of detection (over seven orders of magnitude variation in analyte concentration, from 27.3 mM to 2.73 pM).
  • Room temperature storage and device fabrication.
Status US Provisional application 63/515,583 filed 25-Jul-2023
Available for licensing and/or development partnerships
Development stage Prototype developed and being validated with biological samples

Technology Brief

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