Hemanta Adhikary
Post-Doctoral Fellow
Degrees: | M.Sc. (Tezpur University, India), Ph.D. (MSU Baroda, India) |
Phone: | 613-520-2600 x 2972 |
Email: | Hemanta.adhikary@Carleton.ca |
Office: | Biggar Lab Office: Nesbitt 323 |
Website: | Visit my lab website |
Current Research
My research is primarily focused on the systematic development of peptide-based inhibitors against lysine specific methyltransferase (KMT) and demethylase (KDM) enzymes for their potential use in cancer treatment. I am also interested in the role of PRDM (1-17) proteins in DNA damage repair, synthetic lethal inhibitor screen using BRCA2 deficient prostate cancer cellular model.
Selected Publications
Haghandish, N., Baldwin, R.M., Morettin, A., Dawit, H.T., Adhikary, H., Masson, J.Y., Mazroui, R., Trinkle-Mulcahy, L. and Côté, J., (2019). PRMT7 Methylates Eukaryotic Translation Initiation Factor 2α and Regulates its Role in Stress Granule Formation. Molecular biology of the cell, pp.mbc-E18.
Khanizadeh, S., Hasanvand, B., Nikoo, H.R., Anbari, K., Adhikary, H., Shirkhani, S. and Lashgarian, H.E. (2019). Association between miRNA‐146a rs2910164 (G/C) polymorphism with the susceptibility to chronic HBV infection and spontaneous viral clearance (SVC) in an Iranian population. Journal of medical virology.
Tkáč J*., Xu G*., Adhikary H., Young J.T., Gallo D., Escribano-Díaz C., Krietsch J., Orthwein A., Munro M., Sol W., Al-Hakim A., Lin Z.Y., Jonkers J., Borst P., Brown G.W., Gingras A.C., Rottenberg S., Masson J.Y., Durocher D. (2016). HELB Is a Feedback Inhibitor of DNA End resection. Molecular Cell 61:405-18. * Co-first author.
Adhikary H, Sanghavi P.B., Macwan S.R., Archana G., Naresh Kumar G. (2014). Artificial Citrate Operon Confers Mineral Phosphate Solubilization Ability to diverse Fluorescent Pseudomonads. PLoS ONE9(9): e107554 doi: 10.1371/journal.pone.010755.