Photo of Tim Xing

Tim Xing

Associate Professor

Degrees:B.Sc. (Anhui Normal University), Ph.D. (Leicester Polytechnic, England)
Phone:613-520-2600 x 8981
Email:tim_xing@carleton.ca
Office:Office: 4440L CTTC
Lab: 226 Nesbitt Building

Research

The laboratory focuses on molecular mechanisms of plant disease resistance in wheat, tomato and Arabidopsis. We try to identify and manipulate key signal transduction pathways to enhance plant resistance to pathogen attacks. The mitogen-activated protein kinase (MAPK) pathway is a key pathway in plant defense. Functional genomics and proteomics approaches are applied. The proteins are analyzed by two-dimensional electrophoresis (2DE), matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF), and liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Selected Publications

Fan T, Bykova N, Rampitsch C, Xing T. (2016) Identification and characterization of a serine protease from wheat leaves. Eur. J. Plant Pathol. 146: 293-304. doi: 10.1007/s10658-016-0914-x.

Gao Y, Stebbing JA, Tubei K, Tian LN, Li XQ, Xing, T. (2016) Response of TaFLR MAPKKK to wheat leaf rust and Fusarium head blight and the activation of downstream components. Tropical Plant Pathol. doi: 10.1007/s40858-015-0063-3.

Li XQ, Xing T, Du D. (2016) Identification of top-ranked proteins within a directional protein interaction network using the PageRank algorithm: Applications in humans and plants. Curr. Issues Molec. Biol. 20: 13-28.

Xing T, Wang XJ. (2015) Protoplasts in plant signaling analysis: moving forward in the omics era. Botany 93: 325–332.

Nguyen S, Huang H, Foster BC, Tam TW, Xing T, Smith ML, Arnason JT, Akhtar H. (2014) Antimicrobial and P450 inhibitory properties of common functional foods. J. Pharm. Pharm. Sci. 17: 254 – 265.

Nazemof N, Couroux P, Rampitsch C,Xing T, Robert L. (2014) Proteomic profiling of the triticale stigma. Proteomic profiling reveals insights into Triticeae stigma development and function. Exp.Bot.doi:10.1093/jxb/eru350

Conroy C, Ching J, Gao Y, Wang XJ, Rampitsch C, Xing T. (2013) Knockout of AtMKK1 enhances salt tolerance and modifies metabolic activities inArabidopsisPlant Signal. Behav.8: e24206; dx.doi.org/10.4161/psb.24206.

Wang YH, Zhang LR, Zhang LL, Xing T, Peng JZ, Sun SL, Chen G, Wang XJ.(2013) A novel stress-associated protein SbSAP14 from Sorghum bicolorconfers tolerance to salt stress in transgenic rice. Molec. Breeding 32: 437-449. (DOI 10.1007/s11032-013-9882-4)

Colville A, Alhattab R, Hu M, Labbé H, Xing T, Miki B. (2011) Role of HD2 genes in seed germination and early seedling growth in Arabidopsis.Plant Cell Rep.30:1969–1979.

Gao Y, Liu XW, Stebbing J, He DF,  Laroche A , Gaudet D, Xing T. (2011) TaFLRS, a novel mitogen-activated protein kinase in wheat defense responses. Eur. J. Plant Pathol.131: 643-651.

Xing T, Laroche A. (2011) Revealing plant defense signaling: getting more sophisticated with phosphoproteomics.Plant Signal. Behav.6:1469-1474.

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