Photo of Zachary Patterson

Zachary Patterson

Instructor I

Degrees:Ph.D. (Carleton)
Phone:613-520-2600 x 6041
Office:3301 Health Sciences Building

Eligible to co-supervise at the undergraduate and graduate level. 

Courses taught: NEUR 2200 (Biological Foundations of Behaviour), and NEUR 3306 (Neural Basis of Addiction)

Academic Interests

My academic interests are related to the effects of drugs – particularly novel psychoactive substances and other illicit substances – on the brain, and how these drugs influence human behavior. I am very much interested in the epidemiological study of novel psychoactive substances, such as where these chemicals are coming from, how they are getting into our country, where and how they are being used and by whom, and what approaches we can take to minimize harms associated with these drugs. It is important that we understand the mechanism through which these drugs impact the central nervous system in order to effectively design interventions (be it programs, policies, practice, etc.) to improve the health and safety of Canadians.


Patterson ZR, Hall B & Young MM. (2017). Substance-related harms at Canadian Music Festivals from May to July 2017. Canadian Community Epidemiology Network on Drug Use Bulletin.

Patterson ZR, Young MM & Vaccarino FJ. (2016) “Novel Psychoactive Substances: What Educators Need to Know”. Journal of Clinical Pharmacology & Therapeutics.

MacKay H, Patterson ZR & Abizaid A (2016) “Perinatal Exposure to Low-Dose Bisphenol-A (BPA) Disrupts the Structural and Functional Development of the Hypothalamic Feeding Circuitry” Endocrinology.

Patterson ZR*, Wellman MK*, Mackay H, Darling Joseph, Mani BK, Zigman J, Hougland HL & Abizaid A. (2015) “Novel Regulator of Acylated Ghrelin, CF801, Reduces Weight Gain, Rebound Feeding After a Fast, and Adiposity in Mice” Frontiers in Endocrinology. *Both authors contributed equally to this work.

Agil R, Patterson, ZR, MacKay H, Abizaid A & Hosseinian F (2015). Triticale bran alkylresorcinols enhance resistance to oxidative stress in mice fed a high-fat diet. Foods.

Patton DF, Katsuyama AM, Pavlovski I, Michalik M, Patterson ZR, Parfyonov M, Smit AN, Marchant EG, Chung J, Abizaid A, Storch KF, de la Iglesia H & Mistleberger RE. (2014) “Circadian mechanisms of food anticipatory rhythms in rats fed once or twice daily: clock gene and endocrine correlates” PLoS One. doi: 10.1371/journal.pone.0112451.

Patterson ZR, Parno TJ, Isaacs A & Abizaid A. (2013) “Interruption of Ghrelin Signalling in the PVN Increases High-Fat Diet Intake and Body Weight in C57BL6J Male Mice” Frontiers in Neuroendocrine Science. 10.3389/fnins.2013.00131.

Patterson ZR & Abizaid A. (2013) “Stress Induced Obesity: Lessons From Rodent Models of Stress” Frontiers in Neuroendocrine Science. 10.3389/fnins.2013.00130.

MacKay HA, Khazall R, Patterson ZR, Wellman M & Abizaid A. (2013) “Rats Perinatally Exposed to Food Restriction and High-Fat Diet Show Dierences in Adipose Tissue Gene Expression Under Chronic Caloric Restriction” Adipocyte, 10.1210/en.2012-2044.

Jodayree S, Patterson ZR, Mackay H, Abizaid A & Apollinaire T. (2013) “Blood and Liver Antioxidant Status of Dietary-Induced Obese Mice: Eect of Oat Bran Protein Hydrolysates” Canadian Journal of Physiology & Pharmacology.

Waddington-Lamont E, Patterson ZR, Rodrigues T, Vallejos O, Blum ID & Abizaid A. (2012) “Ghrelin Decient Mice Have Fewer Orexin Cells and Reduced cFos Expression in the Mesolimbic Dopamine Pathway Under a Restricted Feeding Paradigm” Neuroscience 218:12-9.

Patterson ZR & Holahan MR. (2012) “Understanding the Neuroinammatory Response Following Concussion to Develop Treatment Strategies.” Frontiers in Cellular Neuroscience 6(58) doi:10.3389/fncel.2012.0058.

Patterson ZR, Khazall R, MacKay H, Anisman H & Abizaid A. (2012) “Central Ghrelin Signalling Mediates the Metabolic Response of C57BL6 Male Mice to Chronic Social Defeat Stress” Endocrinology; doi:10.1210/en.2012-1834.

Patterson ZR, MacKay H, Khazall R, Patel S, Tsirlin D & Abizaid A. (2012) “Organizational Effects of Perinatal Exposure to Bisphenol-A and Diethylstillbestrol on Arcuate Nucleus Circuitry Controlling Food Intake and Energy Expenditure in Male and Female CD-1 Mice” Endocrinology; doi:10.1210/wn.2012.2044.

Patterson ZR, Ducharme R, Anisman H & Abizaid A. (2010) “Altered Metabolic and Neurochemical Responses to Chronic Unpredictable Stressors in Ghrelin Receptor Decient Mice” European Journal of Neuroscience. 32(4):632-9.

Patterson ZR, Blum ID, Khazall R, Lamont EW, Sleeman MW, Horvath TL & Abizaid A. (2009) “Reduced Anticipatory Locomotor Activity to Scheduled Meals in Ghrelin Receptor Decient Mice” Neuroscience, 164(2):351-9.