|Office:||University of Toronto|
Research: Dr. Wells investigates the mechanisms of drug-induced embryonic death, birth defects and postnatal functional deficits, and identification of those mothers and unborn children who are at high risk. The second area focuses upon embryonic conditions potentially contributing to the subsequent risk for cancer in childhood or later in life. A third area involves the contribution of reactive oxygen species in neurodegenerative diseases, and the role of oxidative and antioxidative pathways determining risk. Complementary to these areas are studies to determine the role of oxidative DNA damage and repair in disease and drug toxicity.